Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | POLG | P54098 | 2/20 | 0.51 |
| ▸ | P2RY2 | P41231 | 6/20 | 0.51 |
| ▸ | P2RY4 | P51582 | 5/20 | 0.51 |
| ▸ | P2RY6 | Q15077 | 3/20 | 0.51 |
| ▸ | POLA1 | P09884 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | CACNA1F | O60840 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | ALB | P02768 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | CACNA1D | Q01668 | 2/20 | 0.40 |
| ▸ | CACNA1S | Q13698 | 2/20 | 0.40 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.40 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.40 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25070750 | 0.89 | POLB (0.69) | POLBPOLGP2RY2P2RY4P2RY6 | |
| SCHEMBL25818685 | 0.85 | POLB (0.48) | POLBPOLGP2RY2P2RY4P2RY6 | |
| SCHEMBL15280907 | 0.83 | POLB (0.49) | POLBPOLGP2RY2P2RY4P2RY6 | |
| SCHEMBL24784384 | 0.83 | POLB (0.49) | POLBPOLGP2RY2P2RY4P2RY6 | |
| SCHEMBL15280768 | 0.83 | POLB (0.49) | POLBPOLGP2RY2P2RY4P2RY6 | |
| SCHEMBL22580358 | 0.82 | POLB (0.50) | POLBPOLGP2RY2P2RY4P2RY6 | |
| SCHEMBL18102345 | 0.82 | POLB (0.58) | POLBPOLGP2RY2P2RY4P2RY6 | |
| SCHEMBL19887010 | 0.81 | POLB (0.46) | POLBPOLGP2RY2P2RY4P2RY6 | |
| SCHEMBL15280754 | 0.81 | POLB (0.46) | POLBPOLGP2RY2P2RY4P2RY6 | |
| SCHEMBL25070863 | 0.81 | P2RY14 (0.58) | P2RY2P2RY4P2RY6P2RY14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230053449-A1 | DC-SIGN ANTIBODY DRUG CONJUGATES | NOVARTIS AG (CH) | 2023-02-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230053449-A1 | DC-SIGN ANTIBODY DRUG CONJUGATES | DCUN1D4, CD14, DCUN1D3 | POLB 4774/4885POLG 4336/4885P2RY2 4533/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.