Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRPF1 | P55201 | 2/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.39 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | NQO2 | P16083 | 4/20 | 0.35 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | CES1 | P23141 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10314053 | 0.75 | BRPF1 (0.41) | BRPF1CA12BRD4CA9KAT2B | |
| SCHEMBL3982412 | 0.74 | BRPF1 (0.38) | BRPF1CA12BRD4CA9KAT2B | |
| SCHEMBL14254506 | 0.73 | BRPF1 (0.40) | BRPF1CA12BRD4CA9KAT2B | |
| SCHEMBL22224593 | 0.71 | BRPF1 (0.39) | BRPF1CA12BRD4CA9KAT2B | |
| SCHEMBL12130341 | 0.70 | SMN1; SMN2 (0.39) | BRPF1CA12BRD4CA9KAT2B | |
| SCHEMBL13560139 | 0.70 | KMT2A (0.38) | BRPF1CA12BRD4CA9KAT2B | |
| SCHEMBL15797658 | 0.70 | KDM4E (0.47) | BRPF1CA12BRD4CA9KAT2B | |
| SCHEMBL15803863 | 0.69 | KMT2A (0.39) | BRPF1CA12BRD4CA9KAT2B | |
| SCHEMBL19693660 | 0.69 | CEL (0.37) | BRPF1CA12BRD4CA9KAT2B | |
| SCHEMBL16093528 | 0.68 | BRPF1 (0.36) | BRPF1CA12BRD4CA9KAT2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023020479-A1 | PARP7 INHIBITOR AND APPLICATION THEREOF | 重庆华森制药股份有限公司 | 2023-02-23 | — | — | WO | disclosed |