Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BIRC2 | Q13490 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.31 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.31 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.31 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | CPN1 | P15169 | 1/20 | 0.30 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.30 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25075121 | 0.84 | BIRC2 (0.38) | BIRC2PKMKDM4ELMNARAB9A | |
| SCHEMBL25075104 | 0.84 | BIRC2 (0.38) | BIRC2PKMKDM4ELMNARAB9A | |
| SCHEMBL25075133 | 0.84 | BIRC2 (0.38) | BIRC2PKMKDM4ELMNARAB9A | |
| SCHEMBL25075313 | 0.84 | BIRC2 (0.38) | BIRC2PKMKDM4ELMNARAB9A | |
| SCHEMBL25075130 | 0.83 | BIRC2 (0.43) | BIRC2PKMKDM4ELMNARAB9A | |
| SCHEMBL25075124 | 0.83 | BIRC2 (0.43) | BIRC2PKMKDM4ELMNARAB9A | |
| SCHEMBL24330246 | 0.81 | GAA (0.47) | BIRC2PKMKDM4ELMNARAB9A | |
| SCHEMBL25075102 | 0.78 | LMNA (0.43) | BIRC2PKMKDM4ELMNARAB9A | |
| SCHEMBL25075490 | 0.78 | KDM4E (0.41) | BIRC2PKMKDM4ELMNARAB9A | |
| SCHEMBL25075446 | 0.78 | PKM (0.40) | PKMKDM4ELMNARAB9AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023023537-A1 | COMPOUNDS AND METHODS FOR THE TARGETED DEGRADATION OF BRUTON'S TYROSINE KINASE | ENDOTARGET INC. (US) | 2023-02-23 | — | — | WO | disclosed |