Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.64 |
| ▸ | CA1 | P00915 | 3/20 | 0.61 |
| ▸ | CA2 | P00918 | 3/20 | 0.61 |
| ▸ | MMP1 | P03956 | 1/20 | 0.61 |
| ▸ | MMP2 | P08253 | 1/20 | 0.61 |
| ▸ | MMP9 | P14780 | 1/20 | 0.61 |
| ▸ | MMP8 | P22894 | 1/20 | 0.61 |
| ▸ | MMP13 | P45452 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.55 |
| ▸ | HPGD | P15428 | 3/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL187561 | 0.80 | GAA (0.70) | GAASMN1; SMN2CA1CA2MMP1 | |
| SCHEMBL7627224 | 0.80 | ALDH1A1 (0.72) | GAASMN1; SMN2CA1CA2MMP1 | |
| SCHEMBL16509308 | 0.78 | GAA (0.67) | GAASMN1; SMN2CA1CA2MMP1 | |
| SCHEMBL30960 | 0.78 | GAA (1.00) | GAASMN1; SMN2CA1CA2MMP1 | |
| Potassium SCHEMBL29525387 | 0.78 | GAA (0.67) | GAASMN1; SMN2CA1CA2MMP1 | |
| SCHEMBL10950543 | 0.78 | GAA (0.67) | GAASMN1; SMN2CA1CA2MMP1 | |
| SCHEMBL15301365 | 0.78 | GAA (0.67) | GAASMN1; SMN2CA1CA2MMP1 | |
| Tosylchloramide SCHEMBL5854126 | 0.76 | GAA (0.64) | GAASMN1; SMN2CA1CA2MMP1 | |
| SCHEMBL11411849 | 0.76 | GAA (0.64) | GAASMN1; SMN2CA1CA2MMP1 | |
| SCHEMBL10531775 | 0.76 | CA2 (0.61) | CA1CA2MMP1MMP2MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 84 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0456509-A1 | Derivatives of 3' - and 3\"-0-desmethyl avermectin compounds | MERCK & CO. INC. (US) | 1991-11-13 | — | — | EP | claimed |
| EP-0103840-B1 | METHOD FOR PREPARING 1,2,3-TRIHETERO 5-MEMBERED HETEROCYCLIC COMPOUNDS | LEDERLE (JAPAN) LTD. (JP) | 1987-03-04 | — | — | EP | claimed |
| US-4540794-A | Method for preparing 5-mercapto-1,2,3-thiadiazole salts | LEDERLE (JAPAN), LTD. (JP) | 1985-09-10 | — | — | US | claimed |
| EP-0103840-A2 | Method for preparing 1,2,3-trihetero 5-membered heterocyclic compounds | LEDERLE (JAPAN) LTD. (JP) | 1984-03-28 | — | — | EP | claimed |
| EP-0009554-B1 | INDANYL DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THESE COMPOUNDS | SCHERING AKTIENGESELLSCHAFT (DE) | 1983-04-27 | — | — | EP | claimed |
| US-4244960-A | HERBICIDES OR ANTIINFLAMMATORY AGENTS | SCHERING, AKTIENGESELLSCHAFT (DE) | 1981-01-13 | — | — | US | claimed |
| JP-56108723-A | — | — | None | — | — | JP | disclosed |
| EP-4297746-A2 | COMPOSITIONS AND METHODS TO IMPROVE THE THERAPEUTIC BENEFIT OF SUBOPTIMALLY ADMINISTERED COMPOUNDS AND THERAPIES FOR THE TREATMENT OF DISEASES | Edison Oncology (US) | 2024-01-03 | — | — | EP | disclosed |
| WO-2023104656-A1 | METHOD FOR SEPARATING GASEOUS CARBON DIOXIDE FROM A GAS MIXTURE | CLIMEWORKS AG (CH) | 2023-06-15 | — | — | WO | disclosed |
| EP-3788042-A1 | BCL-2 INHIBITORS | BeiGene, Ltd. (KY) | 2021-03-10 | — | — | EP | disclosed |
| CN-111851085-A | Foamed resin layer and synthetic leather | 本田技研工业株式会社 | 2020-10-30 | — | — | CN | disclosed |
| WO-2018149419-A1 | MACROCYCLIC BROAD SPECTRUM ANTIBIOTICS | RQX PHARMACEUTICALS, INC. (US) | 2018-08-23 | — | — | WO | disclosed |
| EP-3280715-A1 | NOVEL 5 OR 8-SUBSTITUTED IMIDAZO [1, 5-a]PYRIDINES AS INDOLEAMINE AND/OR TRYPTOPHANE 2, 3-DIOXYGENASES | Beigene, Ltd. (KY) | 2018-02-14 | — | — | EP | disclosed |
| EP-0103840-A2 | Method for preparing 1,2,3-trihetero 5-membered heterocyclic compounds | LEDERLE (JAPAN) LTD. (JP) | 1984-03-28 | — | — | EP | disclosed |
| US-4408060-A | UTERO-EVACUANTS | ORTHO PHARMACEUTICAL CORPORATION (US) | 1983-10-04 | — | — | US | disclosed |
| JP-S56108723-A | PREPARATION OF INDENE DERIVATIVE | IWAKI SEIYAKU KK | 1981-08-28 | — | — | JP | disclosed |
| US-4244960-A | HERBICIDES OR ANTIINFLAMMATORY AGENTS | SCHERING, AKTIENGESELLSCHAFT (DE) | 1981-01-13 | — | — | US | disclosed |
| US-4244960-A | HERBICIDES OR ANTIINFLAMMATORY AGENTS | SCHERING, AKTIENGESELLSCHAFT (DE) | 1981-01-13 | — | — | US | disclosed |
| US-4176188-A | SUBSTITUTED OXEPANE | ORTHO PHARMACEUTICAL CORP. (US) | 1979-11-27 | — | — | US | disclosed |
| US-4102895-A | Oxepanes | ORTHO PHARMACEUTICAL CORPORATION (US) | 1978-07-25 | — | — | US | disclosed |