Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25075754 | 1.00 | PGR (0.33) | PGRARLMNAALDH1A1HPGD | |
| SCHEMBL21974483 | 0.81 | PGR (0.42) | PGRARLMNAALDH1A1HPGD | |
| SCHEMBL8065528 | 0.81 | PGR (0.42) | PGRARLMNAALDH1A1HPGD | |
| SCHEMBL25075655 | 0.80 | — | — | |
| SCHEMBL20029627 | 0.79 | PGR (0.33) | PGRARLMNAALDH1A1HPGD | |
| SCHEMBL23965444 | 0.76 | IDO1 (0.32) | PGRAR | |
| SCHEMBL21245197 | 0.76 | MEN1 (0.32) | PGRAR | |
| SCHEMBL22982351 | 0.76 | MEN1 (0.32) | PGRAR | |
| SCHEMBL23836084 | 0.76 | PGR (0.32) | PGRAR | |
| SCHEMBL26460144 | 0.76 | PGR (0.34) | PGRAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023023631-A1 | INHIBITORS OF CYSTEINE PROTEASES AND METHODS OF USE THEREOF | Pardes Biosciences, Inc. (US) | 2023-02-23 | — | — | WO | disclosed |