Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
| ▸ | PGR | P06401 | 1/20 | 0.32 |
| ▸ | AR | P10275 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22982351 | 0.81 | MEN1 (0.32) | PGRAR | |
| SCHEMBL21245197 | 0.81 | MEN1 (0.32) | PGRAR | |
| SCHEMBL21245017 | 0.78 | CYP19A1 (0.31) | PGRAR | |
| SCHEMBL21244916 | 0.78 | CYP19A1 (0.31) | PGRAR | |
| SCHEMBL21974483 | 0.78 | PGR (0.42) | PGRAR | |
| SCHEMBL8065528 | 0.78 | PGR (0.42) | PGRAR | |
| SCHEMBL25075656 | 0.76 | PGR (0.33) | PGRAR | |
| SCHEMBL25075754 | 0.76 | PGR (0.33) | PGRAR | |
| SCHEMBL20029627 | 0.76 | PGR (0.33) | PGRAR | |
| SCHEMBL21244628 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11161857-B2 | Metal bicyclic amidinates | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2021-11-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11161857-B2 | Metal bicyclic amidinates | SCO2, HAO2, AOC2 | IDO1 716/4885PGR 1699/4885AR 3033/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.