SCHEMBL25075893

SCHEMBL25075893

C[C@@H](OC1CC1)[C@H](NC(=O)OC(C)(C)C)C(=O)O

nearest known ligand 0.43

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CTSK P43235 6/20 0.43
CTSS P25774 5/20 0.43
KMT2A Q03164 4/20 0.41
CA1 P00915 1/20 0.40
CA2 P00918 1/20 0.40
CA7 P43166 1/20 0.40
TSHR P16473 1/20 0.39
CYP2D6 P10635 1/20 0.39
PREP P48147 1/20 0.39
CTSL P07711 3/20 0.38
CTSB P07858 2/20 0.38
ELANE P08246 1/20 0.37
MEN1 O00255 1/20 0.37
ATM Q13315 1/20 0.37
BTK Q06187 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25075892 0.87 CA12 (0.42) CTSKCTSSKMT2ACA1CA2
SCHEMBL13086343 0.80 CTSK (0.38) CTSKCTSSKMT2ACA1CA2
SCHEMBL1536324 0.79 CTSK (0.49) CTSKCTSSKMT2ACA1CA2
SCHEMBL14038647 0.79 CTSK (0.49) CTSKCTSSKMT2ACA1CA2
SCHEMBL1486237 0.79 CTSK (0.49) CTSKCTSSKMT2ACA1CA2
SCHEMBL2418915 0.79 CTSK (0.49) CTSKCTSSKMT2ACA1CA2
SCHEMBL14453090 0.79 CTSK (0.49) CTSKCTSSKMT2ACA1CA2
SCHEMBL6476152 0.79 CTSK (0.49) CTSKCTSSKMT2ACA1CA2
SCHEMBL14039301 0.79 CTSK (0.49) CTSKCTSSKMT2ACA1CA2
SCHEMBL5146050 0.79 CTSK (0.49) CTSKCTSSKMT2ACA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025104230-A1 BENZOXAZOLES AS MODULATORS OF IL-17A SANOFI (FR) 2025-05-22 WO disclosed
EP-4387980-A1 INHIBITORS OF CYSTEINE PROTEASES AND METHODS OF USE THEREOF Pardes Biosciences, Inc. (US) 2024-06-26 EP disclosed
CN-118159548-A Antiviral compounds 安力高医药股份有限公司 2024-06-07 CN disclosed
WO-2023023631-A1 INHIBITORS OF CYSTEINE PROTEASES AND METHODS OF USE THEREOF Pardes Biosciences, Inc. (US) 2023-02-23 WO disclosed
WO-2023023631-A1 INHIBITORS OF CYSTEINE PROTEASES AND METHODS OF USE THEREOF Pardes Biosciences, Inc. (US) 2023-02-23 WO disclosed