Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 5/20 | 0.38 |
| ▸ | CTSS | P25774 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | CTSL | P07711 | 2/20 | 0.36 |
| ▸ | CTSB | P07858 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA7 | P43166 | 1/20 | 0.34 |
| ▸ | BTK | Q06187 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | PREP | P48147 | 1/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25075893 | 0.80 | CTSK (0.43) | CTSKCTSSKMT2ACTSLCTSB | |
| SCHEMBL15879424 | 0.78 | CYP1A2 (0.53) | CTSKCTSSCTSLCTSBTSHR | |
| SCHEMBL17457748 | 0.76 | CTSK (0.46) | CTSKCTSSKMT2ACTSLCTSB | |
| SCHEMBL8306861 | 0.76 | CTSK (0.46) | CTSKCTSSKMT2ACTSLCTSB | |
| SCHEMBL1195750 | 0.76 | CTSK (0.46) | CTSKCTSSKMT2ACTSLCTSB | |
| SCHEMBL22143662 | 0.76 | KMT2A (0.45) | CTSKCTSSKMT2ACTSLCTSB | |
| SCHEMBL6844181 | 0.75 | CTSK (0.35) | CTSKCTSSKMT2ACTSLCTSB | |
| SCHEMBL21896419 | 0.75 | MEN1 (0.35) | KMT2ATSHRMEN1 | |
| SCHEMBL9149904 | 0.75 | MEN1 (0.35) | KMT2ATSHRMEN1 | |
| SCHEMBL4845830 | 0.75 | MEN1 (0.35) | KMT2ATSHRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010118968-A1 | NO-DONOR ASPIRIN DERIVATIVES | NICOX S.A. (FR) | 2010-10-21 | — | — | WO | disclosed |