SCHEMBL25076573

SCHEMBL25076573

CN1CCN(CC(O)CN2c3ccccc3Sc3ccccc32)CC1

nearest known ligand 0.75

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FPR2 P25090 5/20 0.75
MEN1 O00255 1/20 0.72
KMT2A Q03164 1/20 0.72
KDM1A O60341 5/20 0.65
PTGS1 P23219 1/20 0.57
PTGS2 P35354 1/20 0.57
MAPT P10636 4/20 0.53
TSHR P16473 2/20 0.53
BCHE P06276 1/20 0.51
SNCA P37840 1/20 0.51
LMNA P02545 3/20 0.51
TP53 P04637 2/20 0.51
NPSR1 Q6W5P4 2/20 0.51
HCRTR1 O43613 1/20 0.51
ALDH1A1 P00352 1/20 0.51
HTT P42858 1/20 0.51
TDP1 Q9NUW8 1/20 0.51
SLC22A1 O15245 1/20 0.51
ABCB11 O95342 1/20 0.51
CYP1A2 P05177 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21445260 0.87 FPR2 (1.00) FPR2MEN1KMT2AMAPTTSHR
SCHEMBL26001877 0.77 FPR2 (0.85) FPR2MEN1KMT2AMAPTTSHR
Perazine SCHEMBL147165 0.77 KDM1A (1.00) FPR2MEN1KMT2AKDM1APTGS1
Perazine SCHEMBL29390464 0.77 KDM1A (1.00) FPR2MEN1KMT2AKDM1APTGS1
SCHEMBL6859184 0.77 KDM1A (0.94) FPR2MEN1KMT2AKDM1APTGS1
SCHEMBL26001918 0.76 FPR2 (0.73) FPR2MEN1KMT2APTGS1PTGS2
SCHEMBL30534408 0.76 FPR2 (1.00) FPR2MEN1KMT2AMAPTLMNA
SCHEMBL21445226 0.76 FPR2 (1.00) FPR2MEN1KMT2AMAPTLMNA
SCHEMBL7144824 0.76 PTGS1 (0.67) FPR2MEN1KMT2APTGS1PTGS2
Perazine SCHEMBL2237726 0.75 KDM1A (0.97) FPR2MEN1KMT2AKDM1APTGS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023023316-A1 COMPOSITIONS FOR ORGAN AND TISSUE PRESERVATION ALBERT EINSTEIN COLLEGE OF MEDICINE (US) 2023-02-23 WO disclosed