Sugi Predict

Sugi Predict / Compounds / SCHEMBL25076958

SCHEMBL25076958

SCHEMBL25076958

CCCCCCCCCCCCCCCCCCOC[C@H](COP(=O)(O)OC[C@]1(C)C[C@@H](O)[C@H](c2ccc3c(N)ncnn23)O1)OCc1ccc(C#N)nc1

nearest known ligand 0.38

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ POLRMT O00411 1/20 0.36
▸ AKT1 P31749 2/20 0.30
▸ PLCG2 P16885 1/20 0.30
▸ PIK3R1 P27986 1/20 0.30
▸ AKT2 P31751 1/20 0.30
▸ PIK3CA P42336 1/20 0.30
▸ AKT3 Q9Y243 1/20 0.30
▸ GAB1 Q13480 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25077172 0.93 POLRMT (0.36) POLRMTAKT1PLCG2PIK3R1AKT2
SCHEMBL25077063 0.93 POLRMT (0.36) POLRMTAKT1PLCG2PIK3R1AKT2
SCHEMBL25077053 0.91 POLRMT (0.41) POLRMTAKT1PLCG2PIK3R1AKT2
SCHEMBL25764808 0.91 POLRMT (0.41) POLRMTAKT1PLCG2PIK3R1AKT2
SCHEMBL25766893 0.91 POLRMT (0.41) POLRMTAKT1PLCG2PIK3R1AKT2
SCHEMBL25771304 0.90 POLRMT (0.33) POLRMT
SCHEMBL25077321 0.89 POLRMT (0.35) POLRMTAKT1PLCG2PIK3R1AKT2
SCHEMBL25077261 0.89 POLRMT (0.34) POLRMTAKT1PLCG2PIK3R1AKT2
SCHEMBL25077031 0.89 POLRMT (0.34) POLRMTAKT1PLCG2PIK3R1AKT2
SCHEMBL25077289 0.88 POLRMT (0.41) POLRMTAKT1PIK3R1AKT2PIK3CA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023023527-A1 PHOSPHOLIPID COMPOUNDS AND METHODS OF MAKING AND USING THE SAME GILEAD SCIENCES, INC. (US) 2023-02-23 — — WO disclosed
Send feedback