SCHEMBL25076978

SCHEMBL25076978

C=N[C@]1(COP(=O)(O)OC[C@@H](COCCCCCCCCCCCCCCCCCC)OCc2ccc(C#N)c(Cl)c2)O[C@@H](c2ccc3c(N)ncnn23)[C@H](O)[C@@H]1O

nearest known ligand 0.45

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ POLRMT O00411 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25077078 0.92 POLRMT (0.39) POLRMT
SCHEMBL25077367 0.92 POLRMT (0.40) POLRMT
SCHEMBL30476190 0.91 POLRMT (0.39) POLRMT
SCHEMBL25076890 0.91 POLRMT (0.39) POLRMT
SCHEMBL25077280 0.89 POLRMT (0.51) POLRMT
SCHEMBL25773777 0.88 POLRMT (0.37) POLRMT
SCHEMBL25077014 0.86 POLRMT (0.40) POLRMT
SCHEMBL25762546 0.86 POLRMT (0.47) POLRMT
SCHEMBL25077199 0.86 POLRMT (0.41) POLRMT
SCHEMBL25077132 0.86 POLRMT (0.41) POLRMT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023023527-A1 PHOSPHOLIPID COMPOUNDS AND METHODS OF MAKING AND USING THE SAME GILEAD SCIENCES, INC. (US) 2023-02-23 — — WO disclosed
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