Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLRMT | O00411 | 1/20 | 0.41 |
| ▸ | AKT1 | P31749 | 2/20 | 0.30 |
| ▸ | AKT2 | P31751 | 2/20 | 0.30 |
| ▸ | AKT3 | Q9Y243 | 2/20 | 0.30 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.30 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25762079 | 1.00 | POLRMT (0.41) | POLRMTAKT1AKT2AKT3PIK3R1 | |
| SCHEMBL25077289 | 1.00 | POLRMT (0.41) | POLRMTAKT1AKT2AKT3PIK3R1 | |
| SCHEMBL25077215 | 0.95 | POLRMT (0.42) | POLRMT | |
| SCHEMBL25077126 | 0.94 | POLRMT (0.33) | POLRMTAKT1AKT2AKT3PIK3R1 | |
| SCHEMBL25766893 | 0.93 | POLRMT (0.41) | POLRMTAKT1AKT2AKT3PIK3R1 | |
| SCHEMBL25764808 | 0.93 | POLRMT (0.41) | POLRMTAKT1AKT2AKT3PIK3R1 | |
| SCHEMBL25077053 | 0.93 | POLRMT (0.41) | POLRMTAKT1AKT2AKT3PIK3R1 | |
| SCHEMBL25077070 | 0.92 | POLRMT (0.42) | POLRMTAKT1AKT2AKT3PIK3R1 | |
| SCHEMBL25077064 | 0.92 | POLRMT (0.41) | POLRMTAKT1AKT2AKT3PIK3R1 | |
| SCHEMBL25762080 | 0.92 | POLRMT (0.41) | POLRMTAKT1AKT2AKT3PIK3R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023023527-A1 | PHOSPHOLIPID COMPOUNDS AND METHODS OF MAKING AND USING THE SAME | GILEAD SCIENCES, INC. (US) | 2023-02-23 | — | — | WO | disclosed |