SCHEMBL25077270

SCHEMBL25077270

C=N[C@]1(COP(=O)(O)OC[C@@H](COCCCCCCCCCCCCCCCCCC)OCc2ccc(C#N)cc2OC)O[C@@H](c2ccc3c(N)ncnn23)[C@H](O)[C@@H]1O

nearest known ligand 0.45

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ POLRMT O00411 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25077637 0.92 POLRMT (0.45) POLRMT
SCHEMBL25077533 0.92 POLRMT (0.39) POLRMT
SCHEMBL25765689 0.92 POLRMT (0.39) POLRMT
SCHEMBL25077163 0.91 POLRMT (0.39) POLRMT
SCHEMBL30259732 0.91 POLRMT (0.39) POLRMT
SCHEMBL25077294 0.91 POLRMT (0.39) POLRMT
SCHEMBL30259687 0.91 POLRMT (0.39) POLRMT
SCHEMBL25767812 0.87 POLRMT (0.34) POLRMT
SCHEMBL25077253 0.87 POLRMT (0.34) POLRMT
SCHEMBL25766513 0.87 ADK (0.35) POLRMT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023023527-A1 PHOSPHOLIPID COMPOUNDS AND METHODS OF MAKING AND USING THE SAME GILEAD SCIENCES, INC. (US) 2023-02-23 — — WO disclosed
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