SCHEMBL25077355

SCHEMBL25077355

C=NC[C@]1(COP(=O)(O)OC[C@@H](COCCCCCCCCCCCCCCC)OCc2cc(F)cc(C#N)c2)O[C@@H](c2ccc3c(N)ncnn23)[C@H](O)[C@@H]1O

nearest known ligand 0.39

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ POLRMT O00411 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25077225 1.00 POLRMT (0.39) POLRMT
SCHEMBL25077613 1.00 POLRMT (0.39) POLRMT
SCHEMBL25077304 0.96 POLRMT (0.39) POLRMT
SCHEMBL25077379 0.95 POLRMT (0.40) POLRMT
SCHEMBL25771709 0.95 POLRMT (0.40) POLRMT
SCHEMBL25077233 0.95 POLRMT (0.40) POLRMT
SCHEMBL25077320 0.95 POLRMT (0.40) POLRMT
SCHEMBL25077003 0.95 POLRMT (0.40) POLRMT
SCHEMBL25077067 0.91 POLRMT (0.39) POLRMT
SCHEMBL25077255 0.90 POLRMT (0.40) POLRMT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023023527-A1 PHOSPHOLIPID COMPOUNDS AND METHODS OF MAKING AND USING THE SAME GILEAD SCIENCES, INC. (US) 2023-02-23 — — WO disclosed
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