⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2059403 | 0.78 | TSHR (0.40) | — | |
| SCHEMBL27451297 | 0.78 | — | — | |
| SCHEMBL8917128 | 0.78 | — | — | |
| SCHEMBL1100387 | 0.76 | ALDH1A1 (0.40) | — | |
| SCHEMBL7400438 | 0.76 | — | — | |
| SCHEMBL3727886 | 0.75 | — | — | |
| SCHEMBL3883972 | 0.75 | CA12 (0.33) | — | |
| SCHEMBL8982387 | 0.75 | TSHR (0.42) | — | |
| SCHEMBL1100377 | 0.74 | — | — | |
| SCHEMBL8917125 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 148 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021249517-A1 | A MOLECULAR GLUE REGULATING CDK12-DDB1 INTERACTION TO TRIGGER CYCLIN K DEGRADATION | NATIONAL INSTITUTE OF BIOLOGICAL SCIENCES, BEIJING (CN) | 2021-12-16 | — | — | WO | claimed |
| US-8088921-B2 | Method for producing 3-amidinophenylalanine derivatives | WILEX AG (DE) | 2012-01-03 | — | — | US | claimed |
| US-20070043010-A1 | Quinazoline derivatives | ASTRAZENECA UK LIMITED (GB) | 2007-02-22 | — | — | US | claimed |
| EP-1036063-B1 | HETEROARYL AMINOGUANIDINES AND ALKOXYGUANIDINES AND THEIR USE AS PROTEASE INHIBITORS | ORTHO MCNEIL PHARM INC (US) | 2006-11-02 | — | — | EP | claimed |
| WO-2005037797-A1 | SUBSTITUTED PYRAZOLE UREA COMPOUNDS FOR THE TREATMENT OF INFLAMMATION | PHARMACIA CORPORATION (US) | 2005-04-28 | — | — | WO | claimed |
| US-20040116702-A1 | Alkoxylated acyl-and bisacylphoshine derivatives | BASF AKTIENGESELLSCHAFT (DE) | 2004-06-17 | — | — | US | claimed |
| US-6077813-A | 1-(THICARBONYLAMINO),4-(1,2,4-TRIAZOL-1-YL)BENZENES; PRE- AND POSTEMERGENT HERBICIDES; MONO- AND DICOTYLEDONS; SELECTIVE CONTROL | BAYER AKTIENGESELLSCHAFT (DE) | 2000-06-20 | — | — | US | claimed |
| EP-0932604-A1 | SUBSTITUTED 2,4-DIAMINO-1,3,5-TRIAZINES AS HERBICIDES | BAYER AG (DE) | 1999-08-04 | — | — | EP | claimed |
| EP-0915837-A1 | GLYOXYLIC ACID DERIVATIVES | BAYER AG (DE) | 1999-05-19 | — | — | EP | claimed |
| EP-0443059-B1 | 3-(Substituted phenyl)pyrazole derivatives, salts thereof, herbicides therefrom, and process for producing said derivatives or salts | NIHON NOHYAKU CO LTD (JP) | 1998-06-17 | — | — | EP | claimed |
| WO-1998015536-A1 | SUBSTITUTED 2,4-DIAMINO-1,3,5-TRIAZINES AS HERBICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1998-04-16 | — | — | WO | claimed |
| WO-1998003474-A1 | GLYOXYLIC ACID DERIVATIVES | BAYER AKTIENGESELLSCHAFT (DE) | 1998-01-29 | — | — | WO | claimed |
| US-5576444-A | ANTICOAGULANTS | DR. KARL THOMAE GMBH (DE) | 1996-11-19 | — | — | US | claimed |
| WO-1994001401-A1 | HERBICIDAL AND INSECTICIDAL 3-BENZOYL-PYRROLIDIN-2,4-DIONE DERIVATES | BAYER AKTIENGESELLSCHAFT (DE) | 1994-01-20 | — | — | WO | claimed |
| EP-0499416-A2 | Pyridine compounds as angiotensin II antagonists, processes for their preparation and pharmaceutical compositions containing them | ZENECA LIMITED (GB) | 1992-08-19 | — | — | EP | claimed |
| US-4987128-A | ANTIALDOSTERONES, NATRIURETICS | ROUSSEL UCLAF (FR) | 1991-01-22 | — | — | US | claimed |
| EP-0289913-A2 | Parasiticidal agent based on substituted aminomethyl heterocycles | BAYER AG (DE) | 1988-11-09 | — | — | EP | claimed |
| US-4675391-A | IMMUNOREGULATORS | KANTO ISHI PHARMACEUTICAL CO., LTD. (JP) | 1987-06-23 | — | — | US | claimed |
| US-4456752-A | REACTING A HYDRAZINE WITH DIHALOGEN SUBSTITUTED PYRIDO(1,2-A)PYRIMIDINE | CHINOIN GYOGYSZER ES VEGYESZETI TERMEKEK GYARA R.T. (HU) | 1984-06-26 | — | — | US | claimed |
| US-4052377-A | PIGMENTS | BASF AKTIENGESELLSCHAFT (DT) | 1977-10-04 | — | — | US | claimed |