SCHEMBL3883972

SCHEMBL3883972

CC(O[C]=O)C(=O)OC(C)(C)C

nearest known ligand 0.33

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
CA12 O43570 1/20 0.33
CA14 Q9ULX7 1/20 0.33
LMNA P02545 1/20 0.32
KMT2A Q03164 1/20 0.32
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
CA7 P43166 1/20 0.32
DGAT1 O75907 1/20 0.31
NOS1 P29475 2/20 0.31
NOS3 P29474 1/20 0.31
NOS2 P35228 1/20 0.31
CTSS P25774 1/20 0.30
CTSK P43235 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2086712 0.79 CA1 (0.33) CA12CA14LMNAKMT2ACA1
SCHEMBL5706172 0.75 DGAT1 (0.39) CA12CA14LMNAKMT2ACA1
SCHEMBL11207906 0.75
SCHEMBL250780 0.75
SCHEMBL26328504 0.75 CA12 (0.35) CA12CA14LMNAKMT2ACA1
SCHEMBL9738701 0.74 LMNA (0.33) LMNAKMT2A
SCHEMBL2992403 0.74 CTSS (0.34) CTSSCTSK
SCHEMBL17093771 0.73 NOS1 (0.36) CA12CA14LMNAKMT2ACA1
SCHEMBL7277018 0.73 CA12 (0.34) CA12CA14LMNAKMT2ACA1
SCHEMBL10526055 0.73 CA1 (0.37) CA12CA14LMNAKMT2ACA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111601799-B Fused imidazole derivatives as Il-17 modulators UCB生物制药有限责任公司 2023-06-09 CN disclosed
US-11578053-B2 Chemical process for preparing phenylpiperidinyl indole derivatives NOVARTIS AG (CH) 2023-02-14 US disclosed
US-20220169630-A1 CHEMICAL PROCESS FOR PREPARING PHENYLPIPERIDINYL INDOLE DERIVATIVES NOVARTIS AG (CH) 2022-06-02 US disclosed
US-11208398-B2 Chemical process for preparing phenylpiperidinyl indole derivatives NOVARTIS AG (CH) 2021-12-28 US disclosed
CN-112513025-A Chemical process for the preparation of phenylpiperidinylindole derivatives 诺华股份有限公司 2021-03-16 CN disclosed
US-7572898-B2 Process of making an alpha-anomer enriched 2-deoxy-2,2-difluoro-D-ribofuranosyl sulfonate and use thereof for making a beta nucleoside SCINOPHARM TAIWAN, LTD. (TW) 2009-08-11 US disclosed
EP-1891087-A4 PROCESS OF MAKING AN ALPHA-ANOMER ENRICHED 2-DEOXY-2,2-DIFLOURO-D-RIBOFURANOSYL SULFONATE AND USE THEREOF FOR MAKING A BETA NUCLEOSIDE SCINOPHARM TAIWAN LTD (TW) 2008-07-30 EP disclosed
EP-1891087-A1 PROCESS OF MAKING AN ALPHA-ANOMER ENRICHED 2-DEOXY-2,2-DIFLOURO-D-RIBOFURANOSYL SULFONATE AND USE THEREOF FOR MAKING A BETA NUCLEOSIDE ScinoPharm Taiwan, Ltd. (TW) 2008-02-27 EP disclosed
WO-2006132808-A1 PROCESS OF MAKING AN ALPHA-ANOMER ENRICHED 2-DEOXY-2,2-DIFLOURO-D-RIBOFURANOSYL SULFONATE AND USE THEREOF FOR MAKING A BETA NUCLEOSIDE SCINOPHARM TAIWAN, LTD. (TW) 2006-12-14 WO disclosed
US-20060276638-A1 Process of making an alpha-anomer enriched 2-deoxy-2,2-diflouro-d-ribofuranosyl sulfonate and use thereof for making a beta nucleoside SCINOPHARM TAIWAN, LTD. 2006-12-07 US disclosed
US-5256798-A Treating beta-anomer ribofuranosyl sulfonate with source of conjugate anion ELI LILLY AND COMPANY (US) 1993-10-26 US disclosed
US-5252731-A Antibiotics FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1993-10-12 US disclosed
US-5110921-A Bactericides FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1992-05-05 US disclosed
US-5051502-A Process for forming antibiotics UNIVERSITY OF NOTRE DAME DU LAC (US) 1991-09-24 US disclosed
US-4960889-A CEPHALOSPORIN INTERMEDIATES FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1990-10-02 US disclosed
US-4731443-A 7-acylamino-3-vinylcephalosporanic acid derivatives FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1988-03-15 US disclosed
US-4487927-A BACTERICIDES FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1984-12-11 US disclosed
US-4423213-A ANTIBIOTIC FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1983-12-27 US disclosed
EP-0046712-A1 Fluorinated diaminobutane derivatives MERRELL TORAUDE ET COMPAGNIE (FR) 1982-03-03 EP disclosed
US-4071681-A Process for preparing beta-lactam antibiotic substances SANKYO COMPANY LIMITED (JA) 1978-01-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060276638-A1 Process of making an alpha-anomer enriched 2-deoxy-2,2-diflouro-d-ribofuranosyl sulfonate and use thereof for making a beta nucleoside DAD1, DEGS1, DUS2 CA12 180/4885CA14 437/4885LMNA 2229/4885
US-20220169630-A1 CHEMICAL PROCESS FOR PREPARING PHENYLPIPERIDINYL INDOLE DERIVATIVES IDO1, CYP3A7, PAH CA12 3054/4885CA14 2120/4885LMNA 3641/4885
US-11208398-B2 Chemical process for preparing phenylpiperidinyl indole derivatives CYP3A7, CYP3A5, IDO1 CA12 3192/4885CA14 2308/4885LMNA 3569/4885
US-11578053-B2 Chemical process for preparing phenylpiperidinyl indole derivatives IDO1, CYP3A7, PAH CA12 3054/4885CA14 2120/4885LMNA 3641/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.