Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.63 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.63 |
| ▸ | EGFR | P00533 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 4/20 | 0.48 |
| ▸ | RAB9A | P51151 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6895432 | 0.78 | ALDH1A1 (1.00) | ALDH1A1CYP2C19EGFRLMNAMEN1 | |
| SCHEMBL12512971 | 0.78 | ALDH1A1 (0.71) | ALDH1A1CYP2C19EGFRLMNAMEN1 | |
| SCHEMBL6895438 | 0.78 | ALDH1A1 (1.00) | ALDH1A1CYP2C19EGFRLMNAMEN1 | |
| SCHEMBL1503612 | 0.76 | HTT (0.58) | ALDH1A1CYP2C19LMNANPC1RAB9A | |
| SCHEMBL8134361 | 0.74 | ALDH1A1 (0.66) | ALDH1A1CYP2C19EGFRLMNAMEN1 | |
| SCHEMBL12101108 | 0.74 | NPC1 (0.58) | ALDH1A1CYP2C19LMNANPC1RAB9A | |
| SCHEMBL1966601 | 0.73 | EGFR (1.00) | ALDH1A1CYP2C19EGFRLMNAMEN1 | |
| SCHEMBL1966603 | 0.73 | EGFR (1.00) | ALDH1A1CYP2C19EGFRLMNAMEN1 | |
| SCHEMBL2015592 | 0.73 | HTT (0.62) | ALDH1A1CYP2C19LMNANPC1RAB9A | |
| SCHEMBL31563510 | 0.72 | NPC1 (0.50) | ALDH1A1CYP2C19EGFRLMNANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023022497-A1 | SOS1 INHIBITOR AND USE THEREOF | 주식회사 카나프테라퓨틱스 | 2023-02-23 | — | — | WO | disclosed |