Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 6/20 | 0.50 |
| ▸ | RAB9A | P51151 | 6/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 3/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | EGFR | P00533 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6893764 | 0.89 | MAPT (0.50) | NPC1RAB9ASMN1; SMN2HTTGAA | |
| SCHEMBL31563030 | 0.87 | ALDH1A1 (0.43) | NPC1RAB9ASMN1; SMN2HTTGAA | |
| SCHEMBL31080641 | 0.86 | KMT2A (0.48) | NPC1RAB9ASMN1; SMN2HTTMAPT | |
| SCHEMBL31563118 | 0.86 | MAPT (0.45) | NPC1RAB9ASMN1; SMN2HTTGAA | |
| SCHEMBL31563093 | 0.84 | MAPT (0.50) | SMN1; SMN2HTTGAAMAPTLMNA | |
| SCHEMBL14921880 | 0.82 | RAB9A (0.50) | NPC1RAB9ASMN1; SMN2HTTGAA | |
| SCHEMBL31552639 | 0.82 | KCNMA1 (0.49) | NPC1RAB9ASMN1; SMN2GAAMAPT | |
| SCHEMBL4621411 | 0.79 | ALDH1A1 (0.49) | NPC1RAB9ASMN1; SMN2HTTMAPT | |
| SCHEMBL4621414 | 0.79 | ALDH1A1 (0.49) | NPC1RAB9ASMN1; SMN2HTTMAPT | |
| SCHEMBL1503612 | 0.79 | HTT (0.58) | NPC1RAB9ASMN1; SMN2HTTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025077773-A1 | NOVEL TYPE I TOPOISOMERASE INHIBITOR, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 上海翊维康医药有限责任公司 | 2025-04-17 | — | — | WO | disclosed |