Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 3/20 | 0.52 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.46 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | PSMB1 | P20618 | 7/20 | 0.44 |
| ▸ | PSMB9 | P28065 | 6/20 | 0.44 |
| ▸ | PSMB5 | P28074 | 6/20 | 0.44 |
| ▸ | PSMB8 | P28062 | 5/20 | 0.44 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.44 |
| ▸ | BCL2 | P10415 | 1/20 | 0.43 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.43 |
| ▸ | PSMB10 | P40306 | 3/20 | 0.42 |
| ▸ | PSMB2 | P49721 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25079170 | 0.90 | HDAC1 (0.45) | HDAC1MEN1KMT2APSMB1PSMB9 | |
| SCHEMBL30817313 | 0.87 | CA12 (0.48) | PTPN1MEN1KMT2A | |
| SCHEMBL31248684 | 0.85 | MEN1 (0.42) | HDAC1MEN1KMT2ANTSR1POLB | |
| SCHEMBL31248947 | 0.85 | HDAC1 (0.45) | HDAC1MEN1KMT2APSMB1PSMB9 | |
| SCHEMBL31248643 | 0.85 | HDAC1 (0.43) | HDAC1MEN1KMT2APSMB1PSMB9 | |
| SCHEMBL25123736 | 0.85 | KDM4E (0.42) | PTPN1PRMT5MEN1KMT2AADAMTS5 | |
| SCHEMBL25123208 | 0.84 | SUCNR1 (0.42) | MEN1KMT2APOLB | |
| SCHEMBL25123488 | 0.84 | SUCNR1 (0.42) | MEN1KMT2APOLB | |
| SCHEMBL596575 | 0.84 | HDAC1 (0.67) | HDAC1MEN1KMT2AADAMTS5NTSR1 | |
| SCHEMBL25123002 | 0.83 | BCHE (0.48) | PTPN1PRMT5MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023023531-A1 | ESTROGEN RECEPTOR DEGRADERS, PHARMACEUTICAL COMPOSITIONS, AND THERAPEUTIC APPLICATIONS | BIOTHERYX, INC. (US) | 2023-02-23 | — | — | WO | disclosed |