SCHEMBL31248684

SCHEMBL31248684

CC(C)(C)OC(=O)NCc1ccc(-c2ccnc(-c3ccc(OCc4ccccc4)nc3OCc3ccccc3)c2F)cc1

nearest known ligand 0.42

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 2/20 0.42
▸ KMT2A Q03164 2/20 0.42
▸ NTSR1 P30989 1/20 0.41
▸ POLB P06746 1/20 0.41
▸ GPR55 Q9Y2T6 1/20 0.41
▸ AKT1 P31749 1/20 0.41
▸ GRM2 Q14416 1/20 0.40
▸ HDAC1 Q13547 3/20 0.39
▸ MAPT P10636 4/20 0.39
▸ TDP1 Q9NUW8 4/20 0.39
▸ MAPK1 P28482 1/20 0.39
▸ KDM4E B2RXH2 3/20 0.39
▸ NPSR1 Q6W5P4 1/20 0.39
▸ L3MBTL1 Q9Y468 1/20 0.38
▸ NAMPT P43490 3/20 0.37
▸ CNR1 P21554 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25079220 0.85 HDAC1 (0.52) MEN1KMT2ANTSR1POLBGPR55
SCHEMBL31248947 0.83 HDAC1 (0.45) MEN1KMT2ANTSR1POLBGPR55
SCHEMBL31248643 0.80 HDAC1 (0.43) MEN1KMT2ANTSR1POLBGPR55
SCHEMBL25079170 0.79 HDAC1 (0.45) MEN1KMT2ANTSR1POLBGPR55
SCHEMBL31248912 0.75 HDAC1 (0.50) MEN1KMT2ANTSR1POLBGPR55
SCHEMBL30817313 0.75 CA12 (0.48) MEN1KMT2AMAPTKDM4EL3MBTL1
SCHEMBL31248609 0.75 GRM2 (0.51) MEN1KMT2AGPR55AKT1GRM2
SCHEMBL31467422 0.73 CYP2C9 (0.42) MEN1KMT2A
SCHEMBL31467426 0.73 GRIN2B (0.43) MEN1KMT2AAKT1HDAC1CNR1
SCHEMBL31467423 0.73 GRIN2B (0.43) MEN1KMT2AAKT1HDAC1CNR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4720057-A2 COMPOUNDS AND COMPOSITIONS AS CBP/P300 DEGRADERS AND USES THEREOF Oncopia Therapeutics, Inc. D/B/A SK Life Science Labs (US) 2026-04-08 — — EP disclosed
WO-2024249888-A2 COMPOUNDS AND COMPOSITIONS AS CBP/P300 DEGRADERS AND USES THEREOF ONCOPIA THERAPEUTICS, INC. D/B/A SK LIFE SCIENCE LABS (US) 2024-12-05 — — WO disclosed
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