SCHEMBL25080508

SCHEMBL25080508

Cc1cc2c(c(C)c1C)OC(C)(CCC[C@H](C)CCC[C@H](C)CCCC(C)C)CC2

nearest known ligand 0.72

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.72
AKT1 P31749 11/20 0.71
PDPK1 O15530 3/20 0.71
PHLPP1 O60346 3/20 0.71
ILK Q13418 3/20 0.71
MAPT P10636 2/20 0.61
MEN1 O00255 2/20 0.61
KMT2A Q03164 2/20 0.61
GSTP1 P09211 1/20 0.61
TTPA P49638 1/20 0.61
USP2 O75604 1/20 0.61
THRB P10828 1/20 0.61
CYP2C9 P11712 1/20 0.61
CYP2C19 P33261 1/20 0.61
NR1I2 O75469 2/20 0.61
ALOX5 P09917 1/20 0.57
PDE4A P27815 1/20 0.55
PDE3A Q14432 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19604538 1.00 LMNA (0.72) LMNAAKT1PDPK1PHLPP1ILK
SCHEMBL25080531 1.00 LMNA (0.72) LMNAAKT1PDPK1PHLPP1ILK
Gamma-Tocopherol SCHEMBL16430717 0.88 AKT1 (0.91) LMNAAKT1PDPK1PHLPP1ILK
SCHEMBL15441242 0.88 AKT1 (0.91) LMNAAKT1PDPK1PHLPP1ILK
Gamma-Tocopherol SCHEMBL17874900 0.88 AKT1 (0.91) LMNAAKT1PDPK1PHLPP1ILK
Gamma-Tocopherol SCHEMBL8408124 0.88 AKT1 (0.91) LMNAAKT1PDPK1PHLPP1ILK
SCHEMBL25118610 0.88 AKT1 (0.68) LMNAAKT1PDPK1PHLPP1ILK
SCHEMBL25118493 0.88 AKT1 (0.68) LMNAAKT1PDPK1PHLPP1ILK
Gamma-Tocopherol SCHEMBL39640 0.88 AKT1 (0.91) LMNAAKT1PDPK1PHLPP1ILK
Gamma-Tocopherol SCHEMBL29620131 0.88 AKT1 (0.91) LMNAAKT1PDPK1PHLPP1ILK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023023044-A1 ESTERS OF A RETINOID AND TOCOPHEROL OR TERT-BUTYLHYDROQUINONE AND PREPARATIONS THEREOF CONAGEN INC. (US) 2023-02-23 WO disclosed