Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MDM2 | Q00987 | 3/20 | 0.44 |
| ▸ | MDM4 | O15151 | 3/20 | 0.40 |
| ▸ | TP53 | P04637 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | SLC17A5 | Q9NRA2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25081617 | 0.97 | MDM4 (0.42) | MDM2MDM4TP53KMT2APTPN1 | |
| SCHEMBL29238560 | 0.91 | MDM4 (0.42) | MDM2MDM4TP53KMT2ACASP3 | |
| SCHEMBL25081912 | 0.89 | MDM4 (0.49) | MDM2MDM4TP53CASP3SLC17A5 | |
| SCHEMBL29402061 | 0.77 | MDM4 (0.54) | MDM2MDM4TP53KMT2ACASP3 | |
| SCHEMBL29398288 | 0.77 | MDM4 (0.54) | MDM2MDM4TP53KMT2ACASP3 | |
| SCHEMBL29238562 | 0.77 | ACE (0.42) | MDM2MDM4TP53SLC17A5 | |
| SCHEMBL30389933 | 0.77 | ACE (0.42) | MDM2MDM4TP53SLC17A5 | |
| SCHEMBL31647183 | 0.75 | MDM2 (0.56) | MDM2MDM4TP53CASP3SLC17A5 | |
| SCHEMBL16130867 | 0.75 | KMT2A (0.52) | MDM2MDM4TP53KMT2ACASP3 | |
| SCHEMBL608620 | 0.74 | KMT2A (0.54) | MDM2MDM4TP53KMT2APTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023021173-A1 | PROCESS FOR THE PREPARATION OF PEGYLATED ADRENOMEDULLIN, ITS INTERMEDIATES AND USE THEREOF | BAYER AKTIENGESELLSCHAFT (DE) | 2023-02-23 | — | — | WO | disclosed |