SCHEMBL29398288

SCHEMBL29398288

O=C(N[C@H](CSC(c1ccccc1)c1ccccc1)C(=O)O)OCC1c2ccccc2-c2ccccc21

nearest known ligand 0.56

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ MDM4 O15151 3/20 0.54
▸ TP53 P04637 3/20 0.54
▸ SLC17A5 Q9NRA2 1/20 0.52
▸ CASP3 P42574 2/20 0.49
▸ MDM2 Q00987 5/20 0.49
▸ TLR2 O60603 2/20 0.47
▸ KMT2A Q03164 1/20 0.46
▸ ACE P12821 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29402061 1.00 MDM4 (0.54) MDM4TP53SLC17A5CASP3MDM2
SCHEMBL31647183 0.91 MDM2 (0.56) MDM4TP53SLC17A5CASP3MDM2
SCHEMBL25081912 0.88 MDM4 (0.49) MDM4TP53SLC17A5CASP3MDM2
SCHEMBL14788958 0.87 MDM4 (0.59) MDM4TP53SLC17A5CASP3MDM2
SCHEMBL14432835 0.87 MDM4 (0.59) MDM4TP53SLC17A5CASP3MDM2
SCHEMBL29400770 0.86 MDM4 (0.58) MDM4TP53SLC17A5CASP3MDM2
SCHEMBL3436129 0.86 MDM4 (0.58) MDM4TP53SLC17A5CASP3MDM2
SCHEMBL1001473 0.86 MDM4 (0.58) MDM4TP53SLC17A5CASP3MDM2
SCHEMBL16310689 0.85 MDM4 (0.57) MDM4TP53SLC17A5CASP3MDM2
SCHEMBL22154133 0.84 MDM4 (0.56) MDM4TP53SLC17A5CASP3MDM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4425181-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTE Bertis Inc (KR) 2024-09-04 — — EP disclosed
US-20240011979-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTES BERTIS INC. (KR) 2024-01-11 — — US disclosed
CN-116829949-A Compositions for detecting or measuring analytes 伯蒂斯有限公司 2023-09-29 — — CN disclosed
WO-2023075435-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTE 주식회사 베르티스 2023-05-04 — — WO disclosed
US-20220283131-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTES BERTIS CO., LTD. (KR) 2022-09-08 — — US disclosed
WO-2022050529-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTE ㈜베르티스 2022-03-10 — — WO disclosed
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