SCHEMBL29402061

SCHEMBL29402061

O=C(N[C@@H](CSC(c1ccccc1)c1ccccc1)C(=O)O)OCC1c2ccccc2-c2ccccc21

nearest known ligand 0.56

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ MDM4 O15151 3/20 0.54
▸ TP53 P04637 3/20 0.54
▸ SLC17A5 Q9NRA2 1/20 0.52
▸ CASP3 P42574 2/20 0.49
▸ MDM2 Q00987 5/20 0.49
▸ TLR2 O60603 2/20 0.47
▸ KMT2A Q03164 1/20 0.46
▸ ACE P12821 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29398288 1.00 MDM4 (0.54) MDM4TP53SLC17A5CASP3MDM2
SCHEMBL31647183 0.91 MDM2 (0.56) MDM4TP53SLC17A5CASP3MDM2
SCHEMBL25081912 0.88 MDM4 (0.49) MDM4TP53SLC17A5CASP3MDM2
SCHEMBL14788958 0.87 MDM4 (0.59) MDM4TP53SLC17A5CASP3MDM2
SCHEMBL14432835 0.87 MDM4 (0.59) MDM4TP53SLC17A5CASP3MDM2
SCHEMBL29400770 0.86 MDM4 (0.58) MDM4TP53SLC17A5CASP3MDM2
SCHEMBL3436129 0.86 MDM4 (0.58) MDM4TP53SLC17A5CASP3MDM2
SCHEMBL1001473 0.86 MDM4 (0.58) MDM4TP53SLC17A5CASP3MDM2
SCHEMBL16310689 0.85 MDM4 (0.57) MDM4TP53SLC17A5CASP3MDM2
SCHEMBL22154133 0.84 MDM4 (0.56) MDM4TP53SLC17A5CASP3MDM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115894630-A Preparation method of linaclotide 四川轻化工大学 2023-04-04 — — CN claimed
CN-115806607-A Site-directed cyclization method of chlorotoxin polypeptide 哈尔滨吉象隆生物技术有限公司 2023-03-17 — — CN claimed
US-20260115268-A1 Heat-Stable Enterotoxins Mutants as Antidiarrheal Vaccine Antigens VESTLANDETS INNOVASJONSSELSKAP AS (NO) 2026-04-30 — — US disclosed
US-12527853-B2 Heat-stable enterotoxins mutants as antidiarrheal vaccine antigens VESTLANDETS INNOVASJONSSELSKAP AS (VIS) (NO) 2026-01-20 — — US disclosed
CN-118005545-B Small-molecule antibacterial peptide mimics and application thereof 兰州大学 2025-02-18 — — CN disclosed
EP-4425181-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTE Bertis Inc (KR) 2024-09-04 — — EP disclosed
CN-118005545-A Small-molecule antibacterial peptide mimics and application thereof 兰州大学 2024-05-10 — — CN disclosed
US-20240011979-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTES BERTIS INC. (KR) 2024-01-11 — — US disclosed
CN-116829949-A Compositions for detecting or measuring analytes 伯蒂斯有限公司 2023-09-29 — — CN disclosed
WO-2023075435-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTE 주식회사 베르티스 2023-05-04 — — WO disclosed
CN-115894630-A Preparation method of linaclotide 四川轻化工大学 2023-04-04 — — CN disclosed
US-20220283131-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTES BERTIS CO., LTD. (KR) 2022-09-08 — — US disclosed
US-20220249644-A1 Heat-Stable Enterotoxins Mutants as Antidiarrheal Vaccine Antigens VESTLANDETS INNOVASJONSSELSKAP AS (VIS) (NO) 2022-08-11 — — US disclosed
WO-2022050529-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTE ㈜베르티스 2022-03-10 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260115268-A1 Heat-Stable Enterotoxins Mutants as Antidiarrheal Vaccine Antigens SCN8A, SCN9A, VIP MDM4 4004/4885TP53 571/4885SLC17A5 1474/4885
US-12527853-B2 Heat-stable enterotoxins mutants as antidiarrheal vaccine antigens VIP, MLEC, SEC16A MDM4 2800/4885TP53 1413/4885SLC17A5 3568/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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