Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | CDK2 | P24941 | 1/20 | 0.34 |
| ▸ | HRH4 | Q9H3N8 | 4/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | GLP1R | P43220 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.31 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1748325 | 0.80 | GAA (0.48) | TRPM8TDP1GAACDK2HRH4 | |
| SCHEMBL12411085 | 0.78 | MEN1 (0.44) | TRPM8TDP1GAACDK2HRH4 | |
| SCHEMBL9493382 | 0.78 | GAA (0.52) | TRPM8TDP1GAAMEN1KMT2A | |
| SCHEMBL13236189 | 0.78 | TRPM8 (0.42) | TRPM8TDP1HRH4MEN1KMT2A | |
| SCHEMBL4899755 | 0.77 | HRH4 (0.50) | GAAHRH4KMT2AMAPTALDH1A1 | |
| SCHEMBL29394574 | 0.77 | HRH4 (0.50) | GAAHRH4KMT2AMAPTALDH1A1 | |
| SCHEMBL135984 | 0.77 | HRH4 (0.50) | GAAHRH4KMT2AMAPTALDH1A1 | |
| SCHEMBL12127970 | 0.76 | TRPM8 (0.39) | TRPM8TDP1GAACDK2HRH4 | |
| SCHEMBL19225767 | 0.74 | TRPM8 (0.42) | TRPM8TDP1GAACDK2HRH4 | |
| SCHEMBL11680710 | 0.74 | CDK2 (0.35) | TRPM8TDP1GAACDK2HRH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023028338-A2 | MANNOSE 6-PHOSPHATE OR ASGPR RECEPTOR BINDING COMPOUNDS FOR THE DEGRADATION OF EXTRACELLULAR PROTEINS | AVILAR THERAPEUTICS, INC. (US) | 2023-03-02 | — | — | WO | disclosed |