Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 5/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | POLA1 | P09884 | 1/20 | 0.47 |
| ▸ | AURKA | O14965 | 1/20 | 0.43 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.43 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.43 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL135984 | 1.00 | HRH4 (0.50) | HRH4CYP2D6CYP2C19MAPTSMN1; SMN2 | |
| SCHEMBL29394574 | 1.00 | HRH4 (0.50) | HRH4CYP2D6CYP2C19MAPTSMN1; SMN2 | |
| Isopropylamine SCHEMBL28920760 | 0.96 | HRH4 (0.48) | HRH4CYP2D6CYP2C19MAPTSMN1; SMN2 | |
| SCHEMBL11757729 | 0.82 | HRH4 (0.49) | HRH4CYP2D6CYP2C19MAPTSMN1; SMN2 | |
| SCHEMBL10212550 | 0.80 | HRH4 (0.53) | HRH4MAPTKMT2AAURKAPDPK1 | |
| SCHEMBL1748325 | 0.80 | GAA (0.48) | HRH4MAPTPOLBGAAKMT2A | |
| SCHEMBL15757061 | 0.80 | HRH4 (0.44) | HRH4CYP2D6CYP2C19MAPTSMN1; SMN2 | |
| SCHEMBL15757365 | 0.80 | HRH4 (0.44) | HRH4CYP2D6CYP2C19MAPTSMN1; SMN2 | |
| SCHEMBL28043946 | 0.80 | HRH4 (0.44) | HRH4CYP2D6CYP2C19MAPTSMN1; SMN2 | |
| SCHEMBL9315949 | 0.80 | NUDT1 (0.44) | HRH4CYP2D6CYP2C19MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 103 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3906245-B1 | MULTIFUNCTIONAL ORGANOSILICON COMPOUND AND RELATED METHODS, COMPOUNDS, AND COMPOSITIONS | DOW SILICONES CORP (US) | 2024-05-29 | — | — | EP | disclosed |
| EP-3645640-B1 | SILICONE-POLYETHER COPOLYMER, METHOD OF PREPARING SAME, AND SEALANT COMPRISING SAME | DOW SILICONES CORP (US) | 2024-03-06 | — | — | EP | disclosed |
| US-11884821-B2 | Composition, polymer composite article formed therewith, and method of preparing same | DOW SILICONES CORPORATION (US) | 2024-01-30 | — | — | US | disclosed |
| WO-2023215360-A1 | SILICONE-POLYETHER COPOLYMER, SEALANTS COMPRISING SAME, AND RELATED METHODS | DOW SILICONES CORPORATION (US) | 2023-11-09 | — | — | WO | disclosed |
| US-11807775-B2 | Silicone-organic copolymer, sealants comprising same, and related methods | DOW SILICONES CORPORATION (US) | 2023-11-07 | — | — | US | disclosed |
| US-11760841-B2 | Silicone-polycarbonate copolymer, sealants comprising same, and related methods | DOW SILICONES CORPORATION (US) | 2023-09-19 | — | — | US | disclosed |
| EP-3898779-B1 | SILICONE-POLYESTER COPOLYMER, SEALANTS COMPRISING SAME, AND RELATED METHODS | DOW SILICONES CORP (US) | 2023-02-08 | — | — | EP | disclosed |
| EP-3898781-B1 | SILICONE-POLYCARBONATE COPOLYMER, SEALANTS COMPRISING SAME, AND RELATED METHODS | DOW SILICONES CORP (US) | 2023-01-04 | — | — | EP | disclosed |
| US-20220064383-A1 | SILICONE-POLYACRYLATE COPOLYMER, SEALANTS COMPRISING SAME, AND RELATED METHODS | DOW SILICONES CORPORATION | 2022-03-03 | — | — | US | disclosed |
| US-20220064482-A1 | SILICONE-ORGANIC COPOLYMER, SEALANTS COMPRISING SAME, AND RELATED METHODS | DOW SILICONES CORPORATION | 2022-03-03 | — | — | US | disclosed |
| US-20140183398-A1 | Nickel Containing Hydrosilylation Catalysts and Compositions Containing the Catalysts | DOW SILICONES CORPORATION | 2014-07-03 | — | — | US | disclosed |
| US-20140171547-A1 | Bismuth Containing Complex and Condensation Reaction Curable Compositions and Methods for the Preparation and Use of the Compositions | DOW CORNING CORPORATION | 2014-06-19 | — | — | US | disclosed |
| US-20140135517-A1 | Hydrosilylation Reaction Curable Compositions And Methods For Their Preparation And Use | DOW CORNING CORPORATION (US) | 2014-05-15 | — | — | US | disclosed |
| US-20140100347-A1 | Metal Containing Condensation Reaction Catalysts, Methods for Preparing the Catalysts, and Compositions Containing the Catalysts | DOW SILICONES CORPORATION | 2014-04-10 | — | — | US | disclosed |
| US-20140039089-A1 | Compositions Containing Phosphonate Catalysts And Methods For The Preparation And Use Of The Compositions | DOW CORNING CORPORATION (US) | 2014-02-06 | — | — | US | disclosed |
| US-20140018467-A1 | COMPOSITIONS CONTAINING SULFONIC ACID CATALYSTS AND METHODS FOR THE PREPARATION AND USE OF THE COMPOSITIONS | DOW CORNING CORPORATION (US) | 2014-01-16 | — | — | US | disclosed |
| WO-2013052585-A2 | IRON(III) CONTAINING COMPLEX AND CONDENSATION REACTION CATALYSTS, METHODS FOR PREPARING THE CATALYSTS, AND COMPOSITIONS CONTAINING THE CATALYSTS | DOW CORNING CORPORATION (US) | 2013-04-11 | — | — | WO | disclosed |
| WO-2013052588-A1 | IRON(II) CONTAINING COMPLEX AND CONDENSATION REACTION CATALYSTS, METHODS FOR PREPARING THE CATALYSTS, AND COMPOSITIONS CONTAINING THE CATALYSTS | DOW CORNING CORPORATION (US) | 2013-04-11 | — | — | WO | disclosed |
| WO-2013043783-A2 | COBALT CONTAINING HYDROSILYLATION CATALYSTS AND COMPOSITIONS CONTAINING THE CATALYSTS | DOW CORNING CORPORATION (US) | 2013-03-28 | — | — | WO | disclosed |
| US-20080118734-A1 | Coating Compositions | DOW CORNING IRELAND LTD. (IE) | 2008-05-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140135517-A1 | Hydrosilylation Reaction Curable Compositions And Methods For Their Preparation And Use | HIRA, HIRIP3, CROCC | HRH4 54/4885CYP2D6 3558/4885CYP2C19 2180/4885 |
| US-20140183398-A1 | Nickel Containing Hydrosilylation Catalysts and Compositions Containing the Catalysts | HIRA, ALG8, CAD | HRH4 26/4885CYP2D6 4318/4885CYP2C19 2496/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.