SCHEMBL2508482

SCHEMBL2508482

CC=C[Si](C)(C)CCCN(CC)CC

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HRH4 Q9H3N8 2/20 0.33
HRH3 Q9Y5N1 2/20 0.33
ALDH1A1 P00352 1/20 0.33
SIGMAR1 Q99720 1/20 0.32
KDM4E B2RXH2 1/20 0.32
SLC2A1 P11166 1/20 0.32
CHRM2 P08172 1/20 0.31
HTR1A P08908 1/20 0.31
ADRA2A P08913 1/20 0.31
CHRM1 P11229 1/20 0.31
DRD1 P21728 1/20 0.31
SLC6A2 P23975 1/20 0.31
SLC6A4 P31645 1/20 0.31
ADRA1A P35348 1/20 0.31
OPRM1 P35372 1/20 0.31
DRD3 P35462 1/20 0.31
SLC6A3 Q01959 1/20 0.31
KCNH2 Q12809 1/20 0.31
ATP4A P20648 1/20 0.30
ATP4B P51164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2508480 1.00 HRH4 (0.33) HRH4HRH3ALDH1A1SIGMAR1KDM4E
SCHEMBL2509932 0.90 KCNH2 (0.32) CHRM2HTR1AADRA2ACHRM1DRD1
SCHEMBL2509936 0.90 KCNH2 (0.32) CHRM2HTR1AADRA2ACHRM1DRD1
SCHEMBL2499955 0.87
SCHEMBL2499958 0.87
SCHEMBL2509137 0.86 ATP4A (0.32) ATP4AATP4B
SCHEMBL2509135 0.86 ATP4A (0.32) ATP4AATP4B
SCHEMBL2503639 0.86 MAPT (0.32) ATP4AATP4B
SCHEMBL2503635 0.86 MAPT (0.32) ATP4AATP4B
SCHEMBL2508994 0.82 CHRNB2 (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8304488-B2 Conjugated diene polymer, conjugated diene polymer composition, and method for producing conjugated diene polymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-11-06 US disclosed
US-20110245408-A1 CONJUGATED DIENE POLYMER, CONJUGATED DIENE POLYMER COMPOSITION, AND METHOD FOR PRODUCING CONJUGATED DIENE POLYMER SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-10-06 US disclosed
CN-102206304-A Conjugated diene polymer, conjugated diene polymer composition, and method for producing conjugated diene polymer SUMITOMO CHEMICAL CO 2011-10-05 CN disclosed