Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.77 |
| ▸ | MAPT | P10636 | 6/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.69 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.67 |
| ▸ | MEN1 | O00255 | 4/20 | 0.67 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.67 |
| ▸ | LMNA | P02545 | 1/20 | 0.67 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.67 |
| ▸ | HTT | P42858 | 1/20 | 0.65 |
| ▸ | NPC1 | O15118 | 2/20 | 0.63 |
| ▸ | HPGD | P15428 | 1/20 | 0.63 |
| ▸ | RAB9A | P51151 | 1/20 | 0.63 |
| ▸ | GAA | P10253 | 1/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9312707 | 0.87 | POLB (1.00) | POLBMAPTALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL12445438 | 0.86 | POLB (0.83) | POLBMAPTALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL25086 | 0.84 | POLB (0.80) | POLBMAPTALDH1A1SMN1; SMN2KDM4E | |
| Fenacetinol SCHEMBL2850567 | 0.84 | POLB (0.80) | POLBMAPTALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL2853774 | 0.83 | POLB (0.83) | POLBMAPTALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL9842944 | 0.83 | POLB (0.77) | POLBMAPTALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL29270204 | 0.83 | POLB (0.77) | POLBMAPTALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL5808300 | 0.83 | POLB (0.77) | POLBMAPTALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL6424909 | 0.83 | POLB (0.77) | POLBMAPTALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL10576308 | 0.82 | MAPT (0.86) | POLBMAPTALDH1A1SMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006093518-A2 | THIENYL COMPOUNDS FOR TREATING VIRUS-RELATED CONDITIONS | APATH, LLC (US) | 2006-09-08 | — | — | WO | disclosed |