SCHEMBL2508673

SCHEMBL2508673

OB(O)c1ccc(-c2ccc3ccccc3c2)c2ccccc12

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GSTP1 P09211 1/20 0.47
CA1 P00915 1/20 0.44
CA2 P00918 1/20 0.44
HDAC4 P56524 1/20 0.44
HDAC2 Q92769 1/20 0.44
HDAC8 Q9BY41 1/20 0.44
ESR2 Q92731 3/20 0.43
ESR1 P03372 2/20 0.43
SLC6A2 P23975 1/20 0.43
SLC6A4 P31645 1/20 0.43
SLC6A3 Q01959 1/20 0.43
GPR84 Q9NQS5 1/20 0.42
ALOX5 P09917 1/20 0.42
HSD17B1 P14061 1/20 0.41
HSD17B2 P37059 1/20 0.41
AKR1C3 P42330 3/20 0.40
AKR1C2 P52895 3/20 0.40
ERN1 O75460 1/20 0.40
CYP1A2 P05177 1/20 0.40
CYP3A4 P08684 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29710463 1.00 GSTP1 (0.47) GSTP1CA1CA2HDAC4HDAC2
SCHEMBL20622991 0.87 HDAC4 (0.40) GSTP1CA1CA2HDAC4HDAC2
SCHEMBL18306183 0.87 GSTP1 (0.42) GSTP1CA1CA2HDAC4HDAC2
SCHEMBL3193310 0.83 GSTP1 (0.64) GSTP1CA1CA2HDAC4HDAC2
SCHEMBL3193631 0.81 GSTP1 (0.61) GSTP1CA1CA2HDAC4HDAC2
SCHEMBL28547175 0.81 NPC1 (0.54) AKR1C3AKR1C2ERN1CYP3A4
SCHEMBL29410296 0.80 GSTP1 (0.52) GSTP1CA1CA2HDAC4HDAC2
SCHEMBL3686032 0.80 GSTP1 (0.52) GSTP1CA1CA2HDAC4HDAC2
SCHEMBL556400 0.80 HDAC4 (0.45) GSTP1CA1CA2HDAC4HDAC2
SCHEMBL23621117 0.79 GSTP1 (0.47) GSTP1CA1CA2HDAC4HDAC2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240090318-A1 NOVEL ORGANIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME SFC CO., LTD. (KR) 2024-03-14 US disclosed
US-11864460-B2 Organic light emitting device LG CHEM, LTD. (KR) 2024-01-02 US disclosed
EP-4273114-A1 NOVEL ORGANIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME SFC Co., Ltd. (KR) 2023-11-08 EP disclosed
CN-101993445-B Heterocyclic compound and organic light-emitting device including same SAMSUNG DISPLAY CO LTD 2015-02-25 CN disclosed
US-8034256-B2 Naphthalene derivative, material for organic electroluminescence device, and organic electroluminescence device using the same IDEMITSU KOSAN CO., LTD. (JP) 2011-10-11 US disclosed
CN-101993445-A Organic light-emitting device SAMSUNG MOBILE DISPLAY CO LTD 2011-03-30 CN disclosed
US-20090008607-A1 NAPHTHALENE DERIVATIVE, MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE, AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2009-01-08 US disclosed
US-20090008607-A1 NAPHTHALENE DERIVATIVE, MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE, AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2009-01-08 US disclosed
US-20090008607-A1 NAPHTHALENE DERIVATIVE, MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE, AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2009-01-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090008607-A1 NAPHTHALENE DERIVATIVE, MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE, AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME CCNL2, ARL1, CCNA1 GSTP1 2916/4885CA1 2406/4885CA2 2757/4885
US-20240090318-A1 NOVEL ORGANIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME AOX1, PPOX, CYBA GSTP1 624/4885CA1 3033/4885CA2 3226/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.