⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26814189 | 0.78 | SIGMAR1 (0.30) | — | |
| SCHEMBL22306029 | 0.76 | — | — | |
| SCHEMBL24941858 | 0.75 | — | — | |
| SCHEMBL24549375 | 0.75 | GNAI3 (0.33) | — | |
| SCHEMBL22306027 | 0.73 | — | — | |
| SCHEMBL26327839 | 0.73 | — | — | |
| SCHEMBL22302282 | 0.71 | — | — | |
| SCHEMBL25720034 | 0.67 | — | — | |
| SCHEMBL15199211 | 0.67 | — | — | |
| SCHEMBL24250662 | 0.66 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230065463-A1 | COMPOUNDS AND USES THEREOF | FOGHORN THERAPEUTICS INC. | 2023-03-02 | — | — | US | disclosed |