Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25089983 | 1.00 | ALDH1A1 (0.43) | ALDH1A1LMNAKMT2ATP53PKM | |
| SCHEMBL22301099 | 0.99 | ALDH1A1 (0.44) | ALDH1A1LMNAKMT2ATP53PKM | |
| SCHEMBL25090049 | 0.87 | ALDH1A1 (0.44) | ALDH1A1LMNAKMT2ATP53PKM | |
| SCHEMBL25089987 | 0.85 | ALDH1A1 (0.45) | ALDH1A1LMNAKMT2ATP53PKM | |
| SCHEMBL22305725 | 0.85 | TSHR (0.47) | ALDH1A1LMNAKMT2ATSHRCYP3A4 | |
| SCHEMBL22305722 | 0.84 | ALDH1A1 (0.45) | ALDH1A1KMT2ATSHRL3MBTL1EPHX2 | |
| SCHEMBL23589714 | 0.83 | NAMPT (0.39) | ALDH1A1LMNAKMT2ATP53PKM | |
| SCHEMBL23589715 | 0.83 | NAMPT (0.39) | ALDH1A1LMNAKMT2ATP53PKM | |
| SCHEMBL23589692 | 0.83 | NAMPT (0.39) | ALDH1A1LMNAKMT2ATP53PKM | |
| SCHEMBL23589907 | 0.83 | NAMPT (0.39) | ALDH1A1LMNAKMT2ATP53PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230065463-A1 | COMPOUNDS AND USES THEREOF | FOGHORN THERAPEUTICS INC. | 2023-03-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230065463-A1 | COMPOUNDS AND USES THEREOF | VHL, TFEB, BECN1 | ALDH1A1 1358/4885LMNA 172/4885KMT2A 682/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.