Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS2 | P35228 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.43 |
| ▸ | CDK2 | P24941 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | GPR39 | O43194 | 1/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20024991 | 1.00 | NOS2 (0.52) | NOS2RAB9ALMNASMN1; SMN2NPC1 | |
| SCHEMBL26291255 | 1.00 | NOS2 (0.52) | NOS2RAB9ALMNASMN1; SMN2NPC1 | |
| SCHEMBL31690862 | 1.00 | NOS2 (0.52) | NOS2RAB9ALMNASMN1; SMN2NPC1 | |
| SCHEMBL526424 | 0.91 | NOS2 (0.55) | NOS2RAB9ASMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL25492838 | 0.90 | NOS2 (0.47) | NOS2RAB9ALMNASMN1; SMN2NPC1 | |
| Hydrochloric Acid SCHEMBL1919379 | 0.89 | NOS2 (0.54) | NOS2RAB9ASMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL24241831 | 0.84 | NOS2 (0.47) | NOS2RAB9ASMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL16548498 | 0.83 | ALDH1A1 (0.58) | NOS2RAB9ASMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL7919601 | 0.83 | ALDH1A1 (0.54) | NOS2RAB9ALMNASMN1; SMN2NPC1 | |
| SCHEMBL17730325 | 0.82 | MERTK (0.55) | NOS2RAB9ASMN1; SMN2NPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230065740-A1 | CYCLIN-DEPENDENT KINASE INHIBITORS | SPV THERAPEUTICS INC. | 2023-03-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230065740-A1 | CYCLIN-DEPENDENT KINASE INHIBITORS | CDK2, CDK1, CCNK | NOS2 3764/4885RAB9A 2410/4885LMNA 1299/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.