Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1813801 | 0.95 | ALDH1A1 (0.42) | MAPTSMN1; SMN2MAPK1POLBL3MBTL1 | |
| SCHEMBL24605264 | 0.90 | HRH3 (0.49) | MAPTSMN1; SMN2ALDH1A1KCNH2HRH3 | |
| SCHEMBL15947087 | 0.85 | ALDH1A1 (0.52) | MAPTSMN1; SMN2MAPK1POLBL3MBTL1 | |
| SCHEMBL27165410 | 0.85 | ALDH1A1 (0.55) | MAPTSMN1; SMN2MAPK1POLBL3MBTL1 | |
| SCHEMBL9898457 | 0.85 | ALDH1A1 (0.55) | MAPTSMN1; SMN2MAPK1POLBL3MBTL1 | |
| SCHEMBL15947085 | 0.82 | MAPT (0.48) | MAPTSMN1; SMN2MAPK1RAB9AALDH1A1 | |
| SCHEMBL24404033 | 0.82 | MAPT (0.42) | MAPTSMN1; SMN2MAPK1POLBL3MBTL1 | |
| SCHEMBL25954140 | 0.81 | KMT2A (0.41) | MAPTSMN1; SMN2MAPK1RAB9AALDH1A1 | |
| SCHEMBL24620659 | 0.80 | MAPT (0.47) | MAPTSMN1; SMN2MAPK1RAB9AALDH1A1 | |
| SCHEMBL4857099 | 0.80 | MAPT (0.52) | MAPTSMN1; SMN2MAPK1L3MBTL1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3653615-B1 | CHROMENE COMPOUND, CURABLE COMPOSITION COMPRISING SAME, AND OPTICAL ARTICLE COMPRISING CURED PRODUCT FORMED OF CURABLE COMPOSITION | TOKUYAMA CORP (JP) | 2023-03-01 | — | — | EP | disclosed |