Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 8/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | HRH2 | P25021 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25091076 | 0.95 | MAPT (0.41) | ALDH1A1MAPTSMN1; SMN2MAPK1USP2 | |
| SCHEMBL15947087 | 0.89 | ALDH1A1 (0.52) | ALDH1A1MAPTSMN1; SMN2MAPK1USP2 | |
| SCHEMBL27165410 | 0.89 | ALDH1A1 (0.55) | ALDH1A1MAPTSMN1; SMN2MAPK1USP2 | |
| SCHEMBL9898457 | 0.89 | ALDH1A1 (0.55) | ALDH1A1MAPTSMN1; SMN2MAPK1USP2 | |
| SCHEMBL24605264 | 0.89 | HRH3 (0.49) | ALDH1A1MAPTSMN1; SMN2LMNAMEN1 | |
| SCHEMBL15947085 | 0.86 | MAPT (0.48) | ALDH1A1MAPTSMN1; SMN2MAPK1LMNA | |
| SCHEMBL24404033 | 0.86 | MAPT (0.42) | ALDH1A1MAPTSMN1; SMN2MAPK1USP2 | |
| SCHEMBL25954140 | 0.84 | KMT2A (0.41) | ALDH1A1MAPTSMN1; SMN2MAPK1USP2 | |
| SCHEMBL4857099 | 0.84 | MAPT (0.52) | ALDH1A1MAPTSMN1; SMN2MAPK1USP2 | |
| SCHEMBL24620659 | 0.84 | MAPT (0.47) | ALDH1A1MAPTSMN1; SMN2MAPK1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11767467-B2 | Photochromic compound and curable composition containing said photochromic compound | TOKUYAMA CORPORATION (JP) | 2023-09-26 | — | — | US | disclosed |
| US-11767467-B2 | Photochromic compound and curable composition containing said photochromic compound | TOKUYAMA CORPORATION (JP) | 2023-09-26 | — | — | US | disclosed |
| US-20230242809-A1 | PHOTOCHROMIC HYDROXYURETHANE COMPOUND | TOKUYAMA CORPORATION (JP) | 2023-08-03 | — | — | US | disclosed |
| US-20230242809-A1 | PHOTOCHROMIC HYDROXYURETHANE COMPOUND | TOKUYAMA CORPORATION (JP) | 2023-08-03 | — | — | US | disclosed |
| EP-4047030-A1 | PHOTOCHROMIC HYDROXYURETHANE COMPOUND | Tokuyama Corporation (JP) | 2022-08-24 | — | — | EP | disclosed |
| US-20220213050-A1 | CHROMENE COMPOUND AND PHOTOCHROMIC OPTICAL ARTICLE | TOKUYAMA CORPORATION (JP) | 2022-07-07 | — | — | US | disclosed |
| EP-3995493-A1 | CHROMENE COMPOUND AND PHOTOCHROMIC OPTICAL ARTICLE | Tokuyama Corporation (JP) | 2022-05-11 | — | — | EP | disclosed |
| US-20210292641-A1 | PHOTOCHROMIC COMPOUND AND CURABLE COMPOSITION CONTAINING SAID PHOTOCHROMIC COMPOUND | TOKUYAMA CORPORATION (JP) | 2021-09-23 | — | — | US | disclosed |
| US-11066523-B2 | Photochromic polyrotaxane compound and curable composition comprising the photochromic polyrotaxane compound | TOKUYAMA CORPORATION (JP) | 2021-07-20 | — | — | US | disclosed |
| EP-3825346-A1 | PHOTOCHROMIC COMPOUND AND CURABLE COMPOSITION CONTAINING SAID PHOTOCHROMIC COMPOUND | Tokuyama Corporation (JP) | 2021-05-26 | — | — | EP | disclosed |
| US-20200190106-A1 | CHROMENE COMPOUND, CURABLE COMPOSITION COMPRISING THE COMPOUND, AND OPTICAL ARTICLE INCLUDING A CURED BODY OF THE CURABLE COMPOSITION | TOKUYAMA CORPORATION (JP) | 2020-06-18 | — | — | US | disclosed |
| US-20200172681-A1 | PHOTOCHROMIC POLYROTAXANE COMPOUND AND CURABLE COMPOSITION COMPRISING THE PHOTOCHROMIC POLYROTAXANE COMPOUND | TOKUYAMA CORPORATION (JP) | 2020-06-04 | — | — | US | disclosed |
| WO-2020017610-A1 | PHOTOCHROMIC COMPOUND AND CURABLE COMPOSITION CONTAINING SAID PHOTOCHROMIC COMPOUND | 株式会社トクヤマ | 2020-01-23 | — | — | WO | disclosed |
| EP-2494408-B9 | PHOTOCHROMIC MATERIALS | TRANSITIONS OPTICAL INC (US) | 2015-09-02 | — | — | EP | disclosed |
| EP-2494408-B1 | PHOTOCHROMIC MATERIALS | TRANSITIONS OPTICAL INC (US) | 2015-04-15 | — | — | EP | disclosed |
| US-8518305-B2 | Photochromic materials | TRANSITIONS OPTICAL, INC. (US) | 2013-08-27 | — | — | US | disclosed |
| WO-2013086248-A1 | PHOTOCHROMIC MATERIALS THAT INCLUDE INDENO-FUSED NAPHTHOPYRANS | PPG INDUSTRIES, INC. (US) | 2013-06-13 | — | — | WO | disclosed |
| EP-2494408-A1 | PHOTOCHROMIC MATERIALS | Transitions Optical, Inc. (US) | 2012-09-05 | — | — | EP | disclosed |
| US-20110108781-A1 | PHOTOCHROMIC MATERIALS | TRANSITIONS OPTICAL, INC. (US) | 2011-05-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220213050-A1 | CHROMENE COMPOUND AND PHOTOCHROMIC OPTICAL ARTICLE | CRY1, CRY2, TRIP13 | ALDH1A1 779/4885MAPT 3612/4885SMN1; SMN2 2698/4885 |
| US-20110108781-A1 | PHOTOCHROMIC MATERIALS | INCENP, SMCHD1, NEDD8 | ALDH1A1 229/4885MAPT 294/4885SMN1; SMN2 4503/4885 |
| US-20200190106-A1 | CHROMENE COMPOUND, CURABLE COMPOSITION COMPRISING THE COMPOUND, AND OPTICAL ARTICLE INCLUDING A CURED BODY OF THE CURABLE COMPOSITION | INCENP, SMCHD1, ILK | ALDH1A1 2274/4885MAPT 2036/4885SMN1; SMN2 1968/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.