Sugi Predict

Sugi Predict / Compounds / SCHEMBL250915

SCHEMBL250915

SCHEMBL250915

c1ccc(P(c2ccccc2)c2cccc3cccnc23)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KDM4E B2RXH2 4/20 0.48
▸ LMNA P02545 3/20 0.48
▸ MAPT P10636 3/20 0.48
▸ MMP2 P08253 2/20 0.48
▸ TSHR P16473 2/20 0.48
▸ TDP1 Q9NUW8 2/20 0.48
▸ SMN1; SMN2 Q16637 2/20 0.48
▸ GMNN O75496 1/20 0.48
▸ TP53 P04637 1/20 0.48
▸ HSP90AA1 P07900 1/20 0.48
▸ CYP3A4 P08684 1/20 0.48
▸ CYP2D6 P10635 1/20 0.48
▸ MMP9 P14780 1/20 0.48
▸ ALOX15 P16050 1/20 0.48
▸ NFKB1 P19838 1/20 0.48
▸ MMP8 P22894 1/20 0.48
▸ CCR1 P32246 1/20 0.48
▸ THPO P40225 1/20 0.48
▸ MTOR P42345 1/20 0.48
▸ HTT P42858 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27583770 0.98 KDM4E (0.47) KDM4ELMNAMAPTMMP2TSHR
SCHEMBL30073592 0.98 KDM4E (0.47) KDM4ELMNAMAPTMMP2TSHR
SCHEMBL28304874 0.98 KDM4E (0.47) KDM4ELMNAMAPTMMP2TSHR
SCHEMBL16511930 0.96 KDM4E (0.45) KDM4ELMNAMAPTMMP2TSHR
SCHEMBL15186538 0.96 KDM4E (0.48) KDM4ELMNAMAPTMMP2TSHR
SCHEMBL17124489 0.82 MAPT (0.39) KDM4ELMNAMAPTMMP2TSHR
Phenanthroline SCHEMBL6532131 0.82 LMNA (0.67) KDM4ELMNAMAPTMMP2TSHR
SCHEMBL14082047 0.82 MAPT (0.45) KDM4ELMNAMAPTMMP2TSHR
SCHEMBL17961877 0.82 MAPT (0.45) KDM4ELMNAMAPTMMP2TSHR
Phenanthroline SCHEMBL4301719 0.81 LMNA (0.64) KDM4ELMNAMAPTMMP2TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110016051-A Diphenyl -8- quinolyl phosphine and triphenylphosphine mixture cuprous halide complex and its synthetic method, application and device 湖北大学 2019-07-16 — — CN claimed
CN-101747375-B Cooper (I) phosphorescent complexes using 8-phosphinoquinoline derivative as ligand and application thereof FUJIAN MATTER STRUCTURE 2013-08-14 — — CN claimed
CN-101747375-A Cooper (I) phosphorescent complexes using 8-phosphinoquinoline derivative as ligand and application thereof FUJIAN INST RES STR MATTER CAS 2010-06-23 — — CN claimed
CN-110016051-A Diphenyl -8- quinolyl phosphine and triphenylphosphine mixture cuprous halide complex and its synthetic method, application and device 湖北大学 2019-07-16 — — CN disclosed
CN-110016051-A Diphenyl -8- quinolyl phosphine and triphenylphosphine mixture cuprous halide complex and its synthetic method, application and device 湖北大学 2019-07-16 — — CN disclosed
CN-110016051-A Diphenyl -8- quinolyl phosphine and triphenylphosphine mixture cuprous halide complex and its synthetic method, application and device 湖北大学 2019-07-16 — — CN disclosed
CN-108993780-A A kind of hybrid mineral flotation machine using novel copper mine flotation agent 孝感寰誉新材科技有限公司 2018-12-14 — — CN disclosed
EP-2076524-B1 CHIRAL PHOSPHORUS COMPOUND JOHNSON MATTHEY PLC (GB) 2016-04-20 — — EP disclosed
EP-2076524-B1 CHIRAL PHOSPHORUS COMPOUND JOHNSON MATTHEY PLC (GB) 2016-04-20 — — EP disclosed
US-8735583-B2 Chiral phosphorus compound JOHNSON MATTHEY PUBLIC LIMITED CO. (GB) 2014-05-27 — — US disclosed
US-8735583-B2 Chiral phosphorus compound JOHNSON MATTHEY PUBLIC LIMITED CO. (GB) 2014-05-27 — — US disclosed
US-20030065181-A1 Novel chiral phosphorus ligands and the use thereof in the production of optically active products STUDIENGESELLSCHAFT KOHL MBH (DE) 2003-04-03 — — US disclosed
EP-1200452-B1 NOVEL CHIRAL PHOSPHORUS LIGANDS AND THE USE THEREOF IN THE PRODUCTION OF OPTICALLY ACTIVE PRODUCTS STUDIENGESELLSCHAFT KOHLE MBH (DE) 2003-03-26 — — EP disclosed
CN-1398835-A N-P coordinating catalyst for oligomerization of nickel ethylene CHINESE ACAD INST CHEMISTRY (CN) 2003-02-26 — — CN disclosed
EP-1200452-A1 NOVEL CHIRAL PHOSPHORUS LIGANDS AND THE USE THEREOF IN THE PRODUCTION OF OPTICALLY ACTIVE PRODUCTS Studiengesellschaft Kohle mbH (DE) 2002-05-02 — — EP disclosed
WO-2001009147-A1 NOVEL CHIRAL PHOSPHORUS LIGANDS AND THE USE THEREOF IN THE PRODUCTION OF OPTICALLY ACTIVE PRODUCTS STUDIENGESELLSCHAFT KOHLE MBH (DE) 2001-02-08 — — WO disclosed
EP-0307026-B1 PROCESS FOR THE PREPARATION OF A BUTENE SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1992-03-18 — — EP disclosed
EP-0259914-B1 NOVEL CATALYST COMPOSITIONS AND PROCESS FOR OLEFIN/CO COPOLYMERIZATION SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1992-03-04 — — EP disclosed
EP-0307026-A1 Process for the preparation of a butene SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1989-03-15 — — EP disclosed
EP-0259914-A1 Novel catalyst compositions and process for olefin/CO copolymerization SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1988-03-16 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030065181-A1 Novel chiral phosphorus ligands and the use thereof in the production of optically active products P2RY4, P2RY1, PIP5K1C KDM4E 3854/4885LMNA 3145/4885MAPT 4424/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.