Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 5/20 | 0.34 |
| ▸ | LMNA | P02545 | 4/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 5/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | KCNJ6 | P48051 | 2/20 | 0.33 |
| ▸ | KCNJ5 | P48544 | 2/20 | 0.33 |
| ▸ | KCNJ3 | P48549 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21809945 | 0.91 | TSHR (0.38) | ALDH1A1CYP1A2CYP3A4CYP2C19POLB | |
| SCHEMBL21809458 | 0.86 | TSHR (0.38) | ALDH1A1CYP1A2CYP3A4CYP2C19POLB | |
| SCHEMBL21810119 | 0.79 | ALDH1A1 (0.37) | ALDH1A1CYP1A2CYP3A4CYP2C19POLB | |
| SCHEMBL21809668 | 0.76 | TSHR (0.41) | ALDH1A1CYP1A2CYP3A4CYP2C19POLB | |
| SCHEMBL21146204 | 0.70 | ALDH1A1 (0.39) | ALDH1A1CYP1A2CYP3A4CYP2C19POLB | |
| SCHEMBL21809932 | 0.70 | TSHR (0.41) | ALDH1A1TSHRLMNAGAAMAPT | |
| SCHEMBL21146679 | 0.68 | MAOB (0.40) | ALDH1A1CYP1A2CYP3A4CYP2C19POLB | |
| SCHEMBL25091656 | 0.67 | TSHR (0.37) | ALDH1A1CYP1A2CYP3A4CYP2C19POLB | |
| SCHEMBL24946149 | 0.67 | HTT (0.35) | ALDH1A1CYP1A2CYP3A4CYP2C19POLB | |
| SCHEMBL21810055 | 0.66 | SLC10A1 (0.43) | ALDH1A1TSHRLMNAGAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230062975-A1 | HEPATITIS B CAPSID ASSEMBLY MODULATORS | SPRING MILL PHARMA, INC. | 2023-03-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230062975-A1 | HEPATITIS B CAPSID ASSEMBLY MODULATORS | HAVCR2, COPB1, HDLBP | ALDH1A1 3850/4885CYP1A2 2946/4885CYP3A4 2465/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.