Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25096022 | 0.86 | NCF1 (0.38) | LIPA | |
| SCHEMBL25095587 | 0.83 | SMN1; SMN2 (0.41) | — | |
| SCHEMBL19169454 | 0.79 | NCF1 (0.43) | LIPA | |
| SCHEMBL18751697 | 0.77 | LIPA (0.38) | LIPA | |
| SCHEMBL8406312 | 0.77 | LIPA (0.52) | LIPA | |
| SCHEMBL3421354 | 0.77 | — | — | |
| Hydrochloric Acid SCHEMBL18979999 | 0.75 | SLC6A12 (0.40) | — | |
| SCHEMBL13885754 | 0.75 | — | — | |
| SCHEMBL25095612 | 0.74 | NCF1 (0.38) | LIPA | |
| SCHEMBL9662429 | 0.73 | LIPA (0.44) | LIPA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230070613-A1 | PROTEIN TYROSINE KINASE 6 (PTK6) DEGRADATION / DISRUPTION COMPOUNDS AND METHODS OF USE | ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI | 2023-03-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230070613-A1 | PROTEIN TYROSINE KINASE 6 (PTK6) DEGRADATION / DISRUPTION COMPOUNDS AND METHODS OF USE | PTK6, NEK6, GRK6 | LIPA 4070/4885BRD4 1222/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.