SCHEMBL25097092

SCHEMBL25097092

CC(C)[C@H]1CN(Cc2ccccc2)C[C@@H](C)N1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FUCA1 P04066 2/20 0.45
ACHE P22303 1/20 0.45
MEN1 O00255 2/20 0.42
KMT2A Q03164 2/20 0.42
KDM4E B2RXH2 1/20 0.42
SIGMAR1 Q99720 4/20 0.42
MLNR O43193 3/20 0.42
CYP3A4 P08684 2/20 0.42
ALDH1A1 P00352 1/20 0.40
TP53 P04637 1/20 0.40
CYP1A2 P05177 1/20 0.40
CYP2D6 P10635 1/20 0.40
CYP2C9 P11712 1/20 0.40
ALOX15 P16050 1/20 0.40
TSHR P16473 1/20 0.40
HTR2A P28223 1/20 0.40
HTR2C P28335 1/20 0.40
MAPK1 P28482 1/20 0.40
CYP2C19 P33261 1/20 0.40
HTR2B P41595 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29257048 1.00 FUCA1 (0.45) FUCA1ACHEMEN1KMT2AKDM4E
SCHEMBL29257047 1.00 FUCA1 (0.45) FUCA1ACHEMEN1KMT2AKDM4E
SCHEMBL3522692 0.85 FUCA1 (0.55) FUCA1ACHEMEN1KMT2ASIGMAR1
SCHEMBL4279682 0.85 FUCA1 (0.55) FUCA1ACHEMEN1KMT2ASIGMAR1
SCHEMBL3324661 0.85 FUCA1 (0.55) FUCA1ACHEMEN1KMT2ASIGMAR1
SCHEMBL3522693 0.85 FUCA1 (0.55) FUCA1ACHEMEN1KMT2ASIGMAR1
SCHEMBL25097373 0.81 FUCA1 (0.42) FUCA1ACHEMEN1KMT2AKDM4E
SCHEMBL3495257 0.80 FUCA1 (0.46) FUCA1ACHESIGMAR1MLNRCYP3A4
SCHEMBL14085915 0.76 SIGMAR1 (0.51) ACHEMEN1KMT2AKDM4ESIGMAR1
SCHEMBL1189622 0.76 SIGMAR1 (0.51) ACHEMEN1KMT2AKDM4ESIGMAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240409536-A1 COMPOUNDS AND METHODS FOR MODULATING SPLICING REMIX THERAPEUTICS INC. 2024-12-12 US disclosed
CN-118234724-A Compounds and methods for modulating splicing 雷密克斯医疗公司 2024-06-21 CN disclosed
WO-2023034811-A1 COMPOUNDS AND METHODS FOR MODULATING SPLICING REMIX THERAPEUTICS INC. (US) 2023-03-09 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240409536-A1 COMPOUNDS AND METHODS FOR MODULATING SPLICING RBM17, SNRPA, SNRPA1 FUCA1 2700/4885ACHE 3477/4885MEN1 3822/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.