Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 6/20 | 0.38 |
| ▸ | NPC1 | O15118 | 5/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31373301 | 0.85 | KDM4C (0.58) | KDM4CKMT2APOLBTDP1SMN1; SMN2 | |
| SCHEMBL31373302 | 0.85 | KDM4C (0.58) | KDM4CKMT2APOLBTDP1SMN1; SMN2 | |
| SCHEMBL14139047 | 0.81 | ALDH1A1 (0.55) | KDM4CKMT2APOLBSMN1; SMN2ALDH1A1 | |
| SCHEMBL864467 | 0.81 | KMT2A (0.59) | KDM4CKMT2APOLBTDP1SMN1; SMN2 | |
| SCHEMBL19659478 | 0.77 | HDAC1 (0.56) | KMT2ASMN1; SMN2ALDH1A1RAB9ANPC1 | |
| SCHEMBL25097156 | 0.77 | ALDH1A1 (0.39) | KDM4CKMT2APOLBTDP1SMN1; SMN2 | |
| SCHEMBL604399 | 0.77 | GAA (0.54) | KDM4CPOLBTDP1ALDH1A1NPC1 | |
| SCHEMBL17454448 | 0.76 | ALDH1A1 (0.38) | KDM4CKMT2APOLBTDP1SMN1; SMN2 | |
| SCHEMBL15159006 | 0.76 | ALDH1A1 (0.38) | KDM4CKMT2APOLBSMN1; SMN2ALDH1A1 | |
| SCHEMBL11235407 | 0.76 | KDM4C (0.38) | KDM4CKMT2APOLBTDP1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230071620-A1 | PHARMACEUTICAL COMPOUNDS FOR TREATMENT OF MEDICAL DISORDERS | ACHILLION PHARMACEUTICALS, INC. | 2023-03-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230071620-A1 | PHARMACEUTICAL COMPOUNDS FOR TREATMENT OF MEDICAL DISORDERS | CFD, TFPI, CFH | KDM4C 4548/4885KMT2A 4702/4885POLB 2864/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.