Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.35 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.35 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.35 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.35 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19115849 | 0.86 | ALDH1A1 (0.36) | ALDH1A1KDM4EPKMDNM1CA1 | |
| SCHEMBL19116205 | 0.86 | ALDH1A1 (0.36) | ALDH1A1KDM4EPKMDNM1CA1 | |
| SCHEMBL25100347 | 0.86 | ALDH1A1 (0.36) | ALDH1A1KDM4EPKMDNM1CA1 | |
| SCHEMBL21861807 | 0.85 | PAOX (0.36) | ALDH1A1KDM4EPKMDNM1CA1 | |
| SCHEMBL26361221 | 0.83 | ALDH1A1 (0.35) | ALDH1A1KDM4EPKMDNM1CA1 | |
| SCHEMBL26361026 | 0.83 | ALDH1A1 (0.35) | ALDH1A1KDM4EPKMDNM1CA1 | |
| SCHEMBL19116139 | 0.82 | DNM1 (0.36) | ALDH1A1KDM4EPKMDNM1CA1 | |
| SCHEMBL19115711 | 0.82 | DNM1 (0.36) | ALDH1A1KDM4EPKMDNM1CA1 | |
| SCHEMBL20026373 | 0.82 | ALDH1A1 (0.36) | ALDH1A1KDM4EPKMDNM1CA1 | |
| SCHEMBL19116312 | 0.82 | ALDH1A1 (0.36) | ALDH1A1KDM4EPKMDNM1CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4223309-A1 | COMBINATION THERAPY WITH CONTROLLED-RELEASE CNP AGONISTS | Ascendis Pharma Growth Disorders A/S (DK) | 2023-08-09 | — | — | EP | disclosed |
| EP-3518930-B1 | COMBINATION THERAPY WITH CONTROLLED-RELEASE CNP AGONISTS | ASCENDIS PHARMA GROWTH DISORDERS AS (DK) | 2023-03-08 | — | — | EP | disclosed |