Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM5 | P08912 | 3/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 9/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 9/20 | 0.36 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.33 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | DRD1 | P21728 | 1/20 | 0.33 |
| ▸ | DRD4 | P21917 | 1/20 | 0.33 |
| ▸ | DRD5 | P21918 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.32 |
| ▸ | KDR | P35968 | 1/20 | 0.32 |
| ▸ | SDHB | P21912 | 1/20 | 0.32 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25100894 | 0.92 | CHRM5 (0.40) | CHRM5CYP11B1CYP11B2DRD2DRD1 | |
| SCHEMBL25100796 | 0.87 | CHRM5 (0.39) | CHRM5CYP11B1CYP11B2CYP3A4 | |
| SCHEMBL23956293 | 0.86 | DYRK1A (0.36) | CHRM5CYP11B1CYP11B2NR1H2NR1H3 | |
| SCHEMBL23956347 | 0.86 | DYRK1A (0.36) | CHRM5CYP11B1CYP11B2NR1H2NR1H3 | |
| SCHEMBL25100911 | 0.86 | CHRM5 (0.35) | CHRM5CYP11B1CYP11B2NR1H2NR1H3 | |
| SCHEMBL25100950 | 0.86 | CHRM5 (0.36) | CHRM5CYP11B1CYP11B2FGFR3KDR | |
| SCHEMBL21290392 | 0.84 | CYP11B1 (0.47) | CYP11B1CYP11B2DYRK1ACYP3A4 | |
| SCHEMBL25100932 | 0.83 | CYP11B1 (0.47) | CYP11B1CYP11B2CYP3A4 | |
| SCHEMBL21290201 | 0.81 | CYP11B1 (0.44) | CYP11B1CYP11B2CYP3A4 | |
| SCHEMBL21290350 | 0.81 | CYP11B1 (0.44) | CYP11B1CYP11B2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3752512-B1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2023-03-01 | — | — | EP | disclosed |