Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM5 | P08912 | 2/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 10/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 10/20 | 0.36 |
| ▸ | WNT3A | P56704 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.30 |
| ▸ | KDR | P35968 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25100796 | 0.95 | CHRM5 (0.39) | CHRM5CYP11B1CYP11B2CYP3A4 | |
| SCHEMBL23956295 | 0.88 | HSD17B1 (0.37) | CHRM5 | |
| SCHEMBL25100561 | 0.86 | CHRM5 (0.39) | CHRM5CYP11B1CYP11B2CYP3A4FGFR3 | |
| SCHEMBL25100806 | 0.84 | USP1 (0.38) | — | |
| SCHEMBL21289938 | 0.84 | CYP11B1 (0.42) | CYP11B1CYP11B2WNT3ACYP3A4 | |
| SCHEMBL23956284 | 0.83 | ALOX5AP (0.36) | CHRM5CYP11B1CYP11B2 | |
| SCHEMBL25100894 | 0.83 | CHRM5 (0.40) | CHRM5CYP11B1CYP11B2WNT3A | |
| SCHEMBL25100508 | 0.83 | LDHA (0.34) | CHRM5 | |
| SCHEMBL25100764 | 0.82 | CHRM5 (0.36) | CHRM5CYP11B1CYP11B2WNT3ACYP3A4 | |
| SCHEMBL21290201 | 0.80 | CYP11B1 (0.44) | CYP11B1CYP11B2WNT3ACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3752512-B1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2023-03-01 | — | — | EP | disclosed |