SCHEMBL25100609

SCHEMBL25100609

C=C/C=C(\C=C/C)c1cccc(-c2cc3c4ccccc4c(=O)n4c5ccc(-c6cccc(-c7ccccc7)c6)cc5c(c2)c34)c1

nearest known ligand 0.31

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
KMO O15229 1/20 0.31
TSPO P30536 1/20 0.31
BRD4 O60885 1/20 0.31
CNR1 P21554 2/20 0.31
CNR2 P34972 1/20 0.31
CECR2 Q9BXF3 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25100608 0.91 KMO (0.34) KMOTSPOBRD4CNR1CNR2
SCHEMBL17097366 0.85 NPC1 (0.31) TSPOBRD4
SCHEMBL20632499 0.79 MAOB (0.39) TSPOBRD4
SCHEMBL15213890 0.79 MAOB (0.39) TSPOBRD4
SCHEMBL14732295 0.79 MAOB (0.39) TSPOBRD4
SCHEMBL14732257 0.78 MAOB (0.40) TSPOBRD4
SCHEMBL21142693 0.77 MAOB (0.40) TSPOBRD4
SCHEMBL21636126 0.77 MAOB (0.40) TSPOBRD4
SCHEMBL22022438 0.77 MAOB (0.40) TSPOBRD4
SCHEMBL21636032 0.77 MAOB (0.40) TSPOBRD4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3752512-B1 METAL COMPLEXES MERCK PATENT GMBH (DE) 2023-03-01 EP disclosed