SCHEMBL14732257

SCHEMBL14732257

O=c1c2ccccc2c2cc(-c3cc(-c4ccccc4)cc(-c4ccccc4)c3)cc3c4cc(-c5cc(-c6ccccc6)cc(-c6ccccc6)c5)ccc4n1c23

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 1/20 0.40
BRD4 O60885 3/20 0.39
TSPO P30536 1/20 0.39
KDM4E B2RXH2 1/20 0.36
MEN1 O00255 1/20 0.36
ALDH1A1 P00352 1/20 0.36
POLB P06746 1/20 0.36
MAPT P10636 1/20 0.36
HPGD P15428 1/20 0.36
HTT P42858 1/20 0.36
KMT2A Q03164 1/20 0.36
MAPK1 P28482 1/20 0.36
PLA2G2A P14555 2/20 0.35
PLA2G4A P47712 2/20 0.35
FEN1 P39748 1/20 0.35
NR4A2 P43354 2/20 0.35
PIM1 P11309 1/20 0.35
NOTUM Q6P988 1/20 0.34
GLO1 Q04760 1/20 0.34
HSP90AA1 P07900 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15213890 0.98 MAOB (0.39) MAOBBRD4TSPOKDM4EMEN1
SCHEMBL14732295 0.98 MAOB (0.39) MAOBBRD4TSPOKDM4EMEN1
SCHEMBL20632499 0.98 MAOB (0.39) MAOBBRD4TSPOKDM4EMEN1
SCHEMBL20633762 0.98 MAOB (0.40) MAOBBRD4TSPOKDM4EMEN1
SCHEMBL14732255 0.98 MAOB (0.40) MAOBBRD4TSPOKDM4EMEN1
SCHEMBL22022438 0.96 MAOB (0.40) MAOBBRD4TSPOKDM4EMEN1
SCHEMBL21142693 0.96 MAOB (0.40) MAOBBRD4TSPOKDM4EMEN1
SCHEMBL21636032 0.96 MAOB (0.40) MAOBBRD4TSPOKDM4EMEN1
SCHEMBL21636126 0.96 MAOB (0.40) MAOBBRD4TSPOKDM4EMEN1
SCHEMBL26042857 0.96 MAOB (0.40) MAOBBRD4TSPOKDM4EMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 65 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11917903-B2 Metal complexes UDC IRELAND LIMITED (IE) 2024-02-27 US disclosed
US-11917903-B2 Metal complexes UDC IRELAND LIMITED (IE) 2024-02-27 US disclosed
US-20230320191-A1 METAL COMPLEXES MERCK PATENT GMBH (DE) 2023-10-05 US disclosed
US-20230320191-A1 METAL COMPLEXES MERCK PATENT GMBH (DE) 2023-10-05 US disclosed
US-11778907-B2 Composition for organic electronic devices MERCK PATENT GMBH (DE) 2023-10-03 US disclosed
US-11778907-B2 Composition for organic electronic devices MERCK PATENT GMBH (DE) 2023-10-03 US disclosed
US-11659763-B2 Metal complexes MERCK PATENT GMBH 2023-05-23 US disclosed
US-11659763-B2 Metal complexes MERCK PATENT GMBH 2023-05-23 US disclosed
EP-3752512-B1 METAL COMPLEXES MERCK PATENT GMBH (DE) 2023-03-01 EP disclosed
US-11387414-B2 Spirobifluorene compounds for organic electroluminescent devices MERCK PATENT GMBH (DE) 2022-07-12 US disclosed
US-20150340621-A1 ORGANIC ELECTROLUMINESCENT DEVICE MERCK PATENT GMBH (DE) 2015-11-26 US disclosed
US-9139582-B2 Organic electroluminescent devices MERCK PATENT GMBH (DE) 2015-09-22 US disclosed
US-9139582-B2 Organic electroluminescent devices MERCK PATENT GMBH (DE) 2015-09-22 US disclosed
US-20150065730-A1 SPIROBIFLUORENE COMPOUNDS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2015-03-05 US disclosed
US-20150065730-A1 SPIROBIFLUORENE COMPOUNDS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2015-03-05 US disclosed
WO-2014166584-A1 ORGANIC ELECTROLUMINESCENT DEVICE WITH THERMALLY ACTIVATED DELAYED FLUORESCENCE MATERIAL MERCK PATENT GMBH (DE) 2014-10-16 WO disclosed
WO-2014166586-A1 ORGANIC ELECTROLUMINESCENT DEVICE MERCK PATENT GMBH (DE) 2014-10-16 WO disclosed
WO-2014094964-A1 ORGANIC ELECTROLUMINESCENT DEVICE MERCK PATENT GMBH (DE) 2014-06-26 WO disclosed
US-20130053555-A1 ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2013-02-28 US disclosed
US-20130053555-A1 ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2013-02-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230320191-A1 METAL COMPLEXES IMMT, MCU, SOD1 MAOB 2037/4885BRD4 932/4885TSPO 875/4885
US-11387414-B2 Spirobifluorene compounds for organic electroluminescent devices PKD1, PIEZO1, AQP1 MAOB 1088/4885BRD4 1935/4885TSPO 929/4885
US-20130053555-A1 ORGANIC ELECTROLUMINESCENT DEVICES L1CAM, PIEZO1, OR10J3 MAOB 951/4885BRD4 1222/4885TSPO 1056/4885
US-11659763-B2 Metal complexes IMMT, MCU, SOD1 MAOB 2037/4885BRD4 932/4885TSPO 875/4885
US-11917903-B2 Metal complexes NCLN, BICRA, AP3M1 MAOB 3740/4885BRD4 312/4885TSPO 284/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.