Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | THRB | P10828 | 1/20 | 0.54 |
| ▸ | MTOR | P42345 | 1/20 | 0.54 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.54 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.54 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.54 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.53 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.53 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.53 |
| ▸ | SLC28A3 | Q9HAS3 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | CDA | P32320 | 1/20 | 0.51 |
| ▸ | SLC5A2 | P31639 | 5/20 | 0.51 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.51 |
| ▸ | ADK | P55263 | 4/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30186595 | 1.00 | LMNA (0.54) | LMNATHRBMTORMDM2NCOA1 | |
| SCHEMBL155587 | 1.00 | LMNA (0.54) | LMNATHRBMTORMDM2NCOA1 | |
| SCHEMBL147428 | 1.00 | LMNA (0.54) | LMNATHRBMTORMDM2NCOA1 | |
| SCHEMBL219357 | 1.00 | LMNA (0.54) | LMNATHRBMTORMDM2NCOA1 | |
| SCHEMBL30186598 | 1.00 | LMNA (0.54) | LMNATHRBMTORMDM2NCOA1 | |
| SCHEMBL20419148 | 0.98 | LMNA (0.56) | LMNATHRBMTORMDM2NCOA1 | |
| SCHEMBL2981353 | 0.98 | LMNA (0.56) | LMNATHRBMTORMDM2NCOA1 | |
| SCHEMBL23982553 | 0.98 | LMNA (0.56) | LMNATHRBMTORMDM2NCOA1 | |
| SCHEMBL4141706 | 0.98 | LMNA (0.56) | LMNATHRBMTORMDM2NCOA1 | |
| SCHEMBL1777532 | 0.82 | LMNA (0.49) | LMNATHRBMTORMDM2NCOA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023028350-A1 | THERAPEUTIC COMPOSITIONS AND RELATED METHODS | BOYCE THOMPSON INSTITUTE FOR PLANT RESEARCH, INC. (US) | 2023-03-02 | — | — | WO | disclosed |