SCHEMBL18820032

SCHEMBL18820032

O=c1ccn(C2OC(CO)C(O)C(O)C2O)c2ccccc12

nearest known ligand 0.55

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ SLC5A2 P31639 6/20 0.55
▸ SLC5A1 P13866 1/20 0.55
▸ SLC28A1 O00337 1/20 0.54
▸ SLC28A2 O43868 1/20 0.54
▸ SLC29A1 Q99808 1/20 0.54
▸ SLC28A3 Q9HAS3 1/20 0.54
▸ MAPT P10636 1/20 0.52
▸ CDA P32320 1/20 0.52
▸ LMNA P02545 1/20 0.52
▸ THRB P10828 1/20 0.52
▸ MTOR P42345 1/20 0.52
▸ MDM2 Q00987 1/20 0.52
▸ NCOA1 Q15788 1/20 0.52
▸ NCOA3 Q9Y6Q9 1/20 0.52
▸ PYGM P11217 1/20 0.48
▸ ADK P55263 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18517560 1.00 SLC5A2 (0.55) SLC5A2SLC5A1SLC28A1SLC28A2SLC29A1
SCHEMBL17179622 1.00 SLC5A2 (0.55) SLC5A2SLC5A1SLC28A1SLC28A2SLC29A1
SCHEMBL25100657 0.82 LMNA (0.54) SLC5A2SLC5A1SLC28A1SLC28A2SLC29A1
SCHEMBL147428 0.82 LMNA (0.54) SLC5A2SLC5A1SLC28A1SLC28A2SLC29A1
SCHEMBL155587 0.82 LMNA (0.54) SLC5A2SLC5A1SLC28A1SLC28A2SLC29A1
SCHEMBL30186595 0.82 LMNA (0.54) SLC5A2SLC5A1SLC28A1SLC28A2SLC29A1
SCHEMBL219357 0.82 LMNA (0.54) SLC5A2SLC5A1SLC28A1SLC28A2SLC29A1
SCHEMBL30186598 0.82 LMNA (0.54) SLC5A2SLC5A1SLC28A1SLC28A2SLC29A1
SCHEMBL1405594 0.82 SLC5A2 (0.51) SLC5A2SLC5A1SLC28A1SLC28A2SLC29A1
SCHEMBL20419148 0.81 LMNA (0.56) SLC5A2SLC5A1SLC28A1SLC28A2SLC29A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10001487-B2 Glucose derivative, and cell imaging method and imaging agent using said derivative HIROSAKI UNIVERSITY (JP) 2018-06-19 — — US disclosed
US-20170122955-A1 NOVEL GLUCOSE DERIVATIVE, AND CELL IMAGING METHOD AND IMAGING AGENT USING SAID DERIVATIVE HIROSAKI UNIVERSITY (JP) 2017-05-04 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170122955-A1 NOVEL GLUCOSE DERIVATIVE, AND CELL IMAGING METHOD AND IMAGING AGENT USING SAID DERIVATIVE SLC2A4, SLC2A1, UGGT1 SLC5A2 10/4885SLC5A1 7/4885SLC28A1 171/4885
US-10001487-B2 Glucose derivative, and cell imaging method and imaging agent using said derivative SLC2A4, SLC2A1, G6PD SLC5A2 11/4885SLC5A1 7/4885SLC28A1 169/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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