Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 13/20 | 0.77 |
| ▸ | MTNR1B | P49286 | 12/20 | 0.77 |
| ▸ | NQO2 | P16083 | 4/20 | 0.77 |
| ▸ | HTR6 | P50406 | 1/20 | 0.62 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.61 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.59 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.59 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.58 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.58 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.58 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.58 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.58 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.58 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.57 |
| ▸ | HTR2B | P41595 | 2/20 | 0.56 |
| ▸ | HTR2C | P28335 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5144427 | 0.87 | MTNR1A (1.00) | MTNR1AMTNR1BNQO2HTR6AKR1C3 | |
| SCHEMBL25101000 | 0.84 | SPR (0.56) | MTNR1AMTNR1BNQO2HTR6AKR1C3 | |
| SCHEMBL30852855 | 0.84 | MTNR1A (0.78) | MTNR1AMTNR1BNQO2AKR1C3HDAC3 | |
| SCHEMBL1067941 | 0.84 | MTNR1A (0.78) | MTNR1AMTNR1BNQO2AKR1C3HDAC3 | |
| SCHEMBL1309580 | 0.83 | MTNR1A (0.76) | MTNR1AMTNR1BNQO2AKR1C3HDAC3 | |
| SCHEMBL3224617 | 0.83 | MTNR1A (0.76) | MTNR1AMTNR1BNQO2AKR1C3HDAC3 | |
| SCHEMBL27714153 | 0.83 | MTNR1A (0.76) | MTNR1AMTNR1BNQO2AKR1C3HDAC3 | |
| SCHEMBL8049981 | 0.83 | MTNR1A (0.69) | MTNR1AMTNR1BNQO2AKR1C3HDAC3 | |
| SCHEMBL8717163 | 0.82 | MTNR1A (0.74) | MTNR1AMTNR1BNQO2HTR6AKR1C3 | |
| SCHEMBL20911445 | 0.82 | MTNR1A (0.58) | MTNR1AMTNR1BNQO2HTR6AKR1C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023028350-A1 | THERAPEUTIC COMPOSITIONS AND RELATED METHODS | BOYCE THOMPSON INSTITUTE FOR PLANT RESEARCH, INC. (US) | 2023-03-02 | — | — | WO | disclosed |