Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2511735 | 0.95 | CNR2 (1.00) | CNR2CNR1 | |
| SCHEMBL2508145 | 0.95 | CNR2 (1.00) | CNR2CNR1 | |
| SCHEMBL19475381 | 0.95 | CNR2 (1.00) | CNR2CNR1 | |
| Hydrochloric Acid SCHEMBL2506033 | 0.94 | CNR2 (0.98) | CNR2CNR1 | |
| Hydrochloric Acid SCHEMBL2511198 | 0.94 | CNR2 (0.98) | CNR2CNR1 | |
| SCHEMBL12197632 | 0.88 | CNR2 (0.79) | CNR2CNR1 | |
| Hydrochloric Acid SCHEMBL2510844 | 0.87 | CNR2 (0.78) | CNR2CNR1 | |
| SCHEMBL2510095 | 0.86 | CNR2 (0.77) | CNR2CNR1 | |
| SCHEMBL12265320 | 0.86 | CNR2 (0.82) | CNR2CNR1 | |
| SCHEMBL19475522 | 0.84 | CNR2 (0.79) | CNR2CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2552921-B1 | PURINE COMPOUNDS | LILLY CO ELI (US) | 2015-10-07 | — | — | EP | disclosed |
| US-8759360-B2 | Purine compounds | ELI LILLY AND COMPANY (US) | 2014-06-24 | — | — | US | disclosed |
| US-20110245255-A1 | PURINE COMPOUNDS | ELI LILLY AND COMPANY | 2011-10-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110245255-A1 | PURINE COMPOUNDS | P2RX1, P2RX3, P2RX7 | CNR2 380/4885CNR1 465/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.