SCHEMBL25101017

SCHEMBL25101017

CNC(Cc1ccc(N=O)cc1)C(=O)OC

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FPR2 P25090 1/20 0.44
ATM Q13315 2/20 0.43
MIF P14174 1/20 0.43
ALDH1A1 P00352 1/20 0.43
THRB P10828 1/20 0.43
CYP2C9 P11712 1/20 0.43
CYP2C19 P33261 1/20 0.43
HSD17B10 Q99714 1/20 0.43
HDAC1 Q13547 4/20 0.42
HDAC6 Q9UBN7 4/20 0.42
ANPEP P15144 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
NOS3 P29474 1/20 0.42
NOS1 P29475 1/20 0.42
NOS2 P35228 1/20 0.42
ESR1 P03372 1/20 0.42
ESR2 Q92731 1/20 0.42
POLB P06746 1/20 0.42
KMT2A Q03164 1/20 0.41
NPSR1 Q6W5P4 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21417606 0.84 FPR2 (0.46) FPR2ALDH1A1HSD17B10NOS3NOS1
SCHEMBL805214 0.84 FPR2 (0.56) FPR2L3MBTL1
SCHEMBL9907283 0.82 KMT2A (0.42) FPR2ATMMIFALDH1A1THRB
SCHEMBL10076406 0.82 ATM (0.58) ATMALDH1A1THRBCYP2C9CYP2C19
SCHEMBL5614085 0.82 ESR1 (0.61) ATMMIFALDH1A1THRBCYP2C9
SCHEMBL24445702 0.82 ESR1 (0.61) ATMMIFALDH1A1THRBCYP2C9
SCHEMBL5614087 0.82 ESR1 (0.61) ATMMIFALDH1A1THRBCYP2C9
SCHEMBL7859150 0.81 HDAC1 (0.60) ATMALDH1A1THRBCYP2C9CYP2C19
Hydrochloric Acid SCHEMBL7431323 0.81 ESR1 (0.59) ATMMIFALDH1A1THRBCYP2C9
SCHEMBL12379269 0.81 ATM (0.46) ATMALDH1A1THRBCYP2C9CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023028350-A1 THERAPEUTIC COMPOSITIONS AND RELATED METHODS BOYCE THOMPSON INSTITUTE FOR PLANT RESEARCH, INC. (US) 2023-03-02 WO disclosed