Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADAM17 | P78536 | 1/20 | 0.42 |
| ▸ | SCN10A | Q9Y5Y9 | 2/20 | 0.37 |
| ▸ | PON1 | P27169 | 1/20 | 0.35 |
| ▸ | TAS1R3 | Q7RTX0 | 5/20 | 0.34 |
| ▸ | TAS1R1 | Q7RTX1 | 5/20 | 0.34 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.34 |
| ▸ | CYP26B1 | Q9NR63 | 1/20 | 0.34 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | GFER | P55789 | 1/20 | 0.31 |
| ▸ | PIM1 | P11309 | 1/20 | 0.31 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.31 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13677505 | 0.80 | NPC1 (0.45) | ADAM17SCN10APON1CYP26A1CYP26B1 | |
| SCHEMBL12965377 | 0.78 | FLT3 (0.44) | TAS1R3TAS1R1NPC1RAB9AMEN1 | |
| SCHEMBL24352389 | 0.78 | TSHR (0.49) | ADAM17TAS1R3TAS1R1MEN1KMT2A | |
| SCHEMBL25101054 | 0.75 | AAK1 (0.43) | SCN10ATAS1R3TAS1R1HDAC6NPC1 | |
| SCHEMBL14157792 | 0.72 | ADAM17 (0.44) | ADAM17PON1CYP26A1CYP26B1HDAC6 | |
| SCHEMBL6654083 | 0.70 | KDM4E (0.43) | — | |
| SCHEMBL8279310 | 0.70 | DYRK1A (0.47) | ADAM17PON1CYP26A1CYP26B1HDAC6 | |
| SCHEMBL10173405 | 0.70 | ADAM17 (0.43) | ADAM17PON1CYP26A1CYP26B1HDAC6 | |
| SCHEMBL25101058 | 0.69 | SCN10A (0.45) | SCN10AGRIA4 | |
| SCHEMBL25101282 | 0.69 | SCN10A (0.36) | SCN10AGRIA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11591341-B2 | Bicyclic and tricyclic compounds | ALIGOS THERAPEUTICS, INC. (US) | 2023-02-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11591341-B2 | Bicyclic and tricyclic compounds | SLC10A1, PKD1, CYP11B2 | ADAM17 2790/4885SCN10A 586/4885PON1 2109/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.